je, unaruhusiwa kutumia erythromycin na fluconazole kwa pamoja?
Hapana!
Fluconazole huwa na mwingiliano na dawa mbalimbali ikiwa pamoja na warfarin, dawa za kunywa za kupunguza kiwango cha sukari kwenye damu, terfenadine, ergotamine, pimozide, dawa za asili na nyingine.
Fluconazole haipaswi kutumiwa pamoja na erythromycin. Hii ni kutokana na uwezo wake mkubwa wa kuzuia vimeng'enya muhimu vya ini ambavyo hufanya umetaboliwa erythromycin ili kutoka mwilini. Fluconazole inaweza kuzuia umetaboli wa erythromycin mpaka siku 4 hadi 5 baada ya kumaliza dozi ya dawa. Hivyo inashauriwa kutotumia erythromycine mpaka siku 7 baada ya kumaliza dozi ya fluconazole.
Endapo utatumia dawa hizi mbili kwa pamoja, ni rahisi kupata maudhi makubwa/madhara ya erythromycin.
Rejea za mada hii;
Drugs.com. Fluconazole vs erythromycin. https://www.drugs.com/tips/fluconazole-patient-tips. Imechukuliwa 10.05.2022
Ray WA, Murray KT, Meredith S, Narasimhulu SS, Hall K, Stein CM. Oral erythromycin and the risk of sudden death from cardiac causes. N Engl J Med 2004 Sep 9;351(11):1089-96.
Diflucan (fluconazole) US prescribing information. Pfizer Inc. March, 2020.
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