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By ULY CLINIC

 

Acute Epiglottitis (AE)

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Introduction

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Epiglottitis is an acute infectious inflammation of the epiglottis, supraglottic and hypopharynx which occurs both in children and adults. It is commonly caused by Haemophilus influenzae. Epiglottitis is a potentially lethal condition especially in children. Edema of the epiglottis may cause acute airway obstruction. 

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Diagnostic Criteria

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  • Throat pain and difficulty in swallowing

  • Drooling

  • Husky voice

  • Fever often high and with chills

  • Patient prefers sitting posture with an extended neck

  • Laborious inspiration

  • Cough in some cases 

  • Anxiety 

 

Investigations:

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Plain X-ray of the neck, lateral view characteristically presents with a positive thumb sign (edematous epiglottis). 

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Non-Pharmacological Treatment:

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  • Immediate hospitalization, preferably in the ICU

  • Transportation: sitting, with oxygen supplementation

  • Be prepared to treat respiratory failure (intubation or tracheotomy)  

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Pharmacological Treatment

 

  • Phenoxymethylpenicillin (PO) 500mg 8 hourly for 7 days. Children up to 5 years: 6 mg/kg 6 hourly for 10 days    

OR

  • Azithromycin (PO) 500mg once daily for 3 days. Children: 10mg/kg once daily for 3 days     

OR

  •  Amoxicillin/Clavulanic acid (PO) Adults: 625mg (500mg amoxicillin+125mg Clavulanic acid) 8 hourly for 7 days  Children: 375mg (250mg amoxicillin+125 Clavulanic acid) 12 hourly for 7 days;     

AND

  • Paracetamol (PO) 1gm 8hourly until fever is controlled. Children: 10 mg/kg body weight 8 hourly 

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Updated on, 30.10.2020

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References

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1. STG 

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