By ULY CLINIC

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MALARIA  

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Malaria is a disease caused by the plasmodium parasite that is transmitted by the bite of an infected female anopheles mosquito. 

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UNCOMPLICATED MALARIA

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Uncomplicated malaria is defined as symptomatic malaria without signs of severity or evidence (clinical or laboratory) of vital organ dysfunction. 

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Diagnostic Criteria

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• Fever

• Hheadache

• Joint pains

• Malaise

• Vomiting

• Diarrhea

• Body ache, body weakness

• Poor appetite

• Pallor, enlarged spleen 

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Investigations

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The clinical features listed above are not specific for malaria and can be found in several other febrile conditions. Therefore, it is necessary to confirm malaria parasites infection and investigate for other causes of febrile illness.

 

Parasite-based diagnosis is recommended for all patients presenting with

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Signs and symptoms of malaria.

 

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The recommended investigations are:

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• Quality malaria microscopy or 

• Quality malaria Rapid Diagnostic Tests (mRDTs)  

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Note: It is compulsory to test and confirm all suspected malaria patients. Give antimalarial only to those who test positive

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Non-Pharmacological Management

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• Continue with feeding and fluid intake

• Followed up immediately if the condition worsens or on the fourth day if symptoms persist. 

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Pharmacological Treatment

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Drug of choice for treatment of uncomplicated malaria is:

Artemether-Lumefantrine (AL), which is a fixed formulation of artemether 20mg and lumefantrine 120mg or dispersible tablets for paediatric use, also with a fixed formulation of artemether 20 mg and lumefantrine 120mg

 

Dosage regimen for AL (artemether 20mg/lumefantrine 120mg)  

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Dosage regimen for AL (artemether 20mg/lumefantrine 120mg)