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ULY CLINIC
ULY CLINIC
17 Mei 2025, 12:04:06
Aphasia

Aphasia, also known as dysphasia, is a neurological disorder characterized by impairment in the expression or comprehension of spoken and written language. It reflects damage to the brain's language centers, typically located in the dominant (usually left) hemisphere. Aphasia can range from mild communication difficulties to complete inability to use or understand language, profoundly impacting patient quality of life. Understanding the types, causes, clinical presentation, and management is essential for health professionals to optimize patient outcomes.
Pathophysiology and types of Aphasia
Aphasia results from damage to key brain areas involved in language processing, predominantly:
Broca’s area: Adjacent to the motor cortex, responsible for speech production.
Wernicke’s area: Center for language comprehension, situated near the auditory cortex.
Arcuate fasciculus: A nerve bundle connecting Broca’s and Wernicke’s areas, enabling speech repetition.
Types of aphasia – Summary table 1
Type | Location of Lesion | Signs and Symptoms |
Anomic Aphasia | Temporal-parietal area; may extend to angular gyrus; often poorly localized | - Fluent speech lacking meaningful content - Word-finding difficulty, circumlocution - Understanding of language relatively intact - Rare paraphasias |
Broca's Aphasia (Expressive) | Broca’s area (3rd frontal convolution, usually in left hemisphere) | - Nonfluent, effortful speech - Limited vocabulary, simple sentence construction - Cannot repeat words/phrases - Relatively good comprehension - Often hemiparetic - Recognizes own errors (if Wernicke’s intact) |
Global Aphasia | Broca’s and Wernicke’s areas | - Severe impairment in both understanding and producing speech - Cannot repeat or follow directions - Occasional jargon or paraphasias |
Wernicke's Aphasia (Receptive) | Wernicke’s area (posterior/superior temporal lobe) | - Fluent, often rapid and rambling speech - Poor comprehension of spoken and written language - Cannot repeat words/phrases - Paraphasias and anomia - Unaware of errors |
Based on the lesion location and severity, aphasia is classified as:
Broca’s aphasia: Non-fluent speech with relatively preserved comprehension.
Wernicke’s aphasia: Fluent but often nonsensical speech with poor comprehension.
Anomic aphasia: Difficulty naming objects; often improves over time.
Global aphasia: Severe impairment of both expression and comprehension; usually irreversible.
Etiology
Aphasia commonly arises due to te following medical condition as described in table 2
Medical causes of aphasia – Summary table 2
Condition | Type of Aphasia | Onset | Associated Signs & Symptoms |
Alzheimer’s Disease | Anomic → Global (progressive) | Insidious | Memory loss, poor judgment, behavioral changes, myoclonus, rigidity, late incontinence |
Brain Abscess | Any type | Insidious | Hemiparesis, ataxia, facial weakness, increased intracranial pressure (ICP) |
Brain Tumor | Any type (progressive) | Progressive | Behavioral/memory changes, weakness, seizures, hallucinations, visual deficits, ↑ICP |
Creutzfeldt-Jakob Disease | Aphasia with dementia | Rapid onset | Myoclonus, ataxia, paralysis, visual disturbances, rapid decline in cognition |
Encephalitis | Usually transient | Sudden | Fever, headache, vomiting, seizures, stupor/coma, nystagmus, ocular palsies, facial weakness |
Head Trauma | Any type | Sudden | Blurred vision, headache, CSF leak, paresis, behavior changes, ↑ICP |
Seizures | Transient (postictal) | Sudden | Confusion, brief language dysfunction if language areas involved |
Stroke | Wernicke’s, Broca’s, Global | Sudden | Hemiparesis, ↓LOC, hemianopsia, paresthesia, sensory loss |
Transient Ischemic Attack (TIA) | Any type (resolves < 24 hrs) | Sudden/temporary | Hemiparesis, hemianopsia, paresthesia, dizziness, confusion |
Clinical presentation
Patients with aphasia present with:
Impaired speech fluency or comprehension depending on aphasia type.
Associated neurological deficits such as hemiparesis, ataxia, or cranial nerve abnormalities.
Signs of increased intracranial pressure (ICP) in cases of tumors or abscesses: vomiting, altered consciousness, pupillary changes.
Confusion, disorientation, or frustration due to communication difficulties.
It is important to differentiate aphasia from dysarthria and speech apraxia, which affect speech production without language impairment.
Diagnostic evaluation
History and Physical Examination: Obtain history from family if needed; assess language function, neurological status, and vital signs.
Neuroimaging:
CT or MRI to detect stroke, tumors, or hemorrhage.
Angiography in vascular pathology.
Functional Assessments:
Speech and language evaluation by a speech pathologist.
Electroencephalogram (EEG) if seizures suspected.
Laboratory Tests:
Infection markers in encephalitis or abscess.
Blood tests for metabolic or systemic causes.
Endoscopic or other specialized assessments if indicated.
Emergency interventions
Monitor and manage signs of increased ICP using mannitol and supportive care.
Prepare for emergency neurosurgical interventions if indicated.
Stabilize airway, breathing, and circulation.
Address underlying cause promptly (e.g., thrombolysis for stroke if within therapeutic window).
Management
Acute phase: Treat underlying cause (e.g., stroke, infection, tumor).
Supportive care: Ensure patient safety, nutrition, hydration, and prevention of complications.
Speech and language therapy: Early referral to speech pathologists to improve communication.
Psychological support: Address depression and frustration; educate family and caregivers.
Communication aids: Use nonverbal tools like communication cards, gestures, and simple language.
Risk factor modification: Manage hypertension, diabetes, smoking cessation to prevent recurrent stroke.
Special considerations
Patients may show confusion or disorientation; reorient frequently.
Expect emotional outbursts linked to frustration; respond gently and supportively.
Avoid speaking loudly or slowly with a condescending tone; aphasia is a language disorder, not a hearing or intellectual problem.
Ensure visual and dental aids are used to facilitate communication.
Patient and family counseling
Educate on the nature of aphasia and prognosis.
Train families on alternative communication strategies and patience.
Stress importance of rehabilitation adherence and risk factor control.
Conclusion
Aphasia is a complex disorder necessitating multidisciplinary care. Prompt recognition, thorough evaluation, targeted treatment of underlying causes, and supportive rehabilitation can significantly improve functional outcomes. Health professionals play a vital role in diagnosis, emergency management, ongoing therapy coordination, and patient-centered communication to enhance quality of life.
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