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ULY CLINIC
ULY CLINIC
9 Septemba 2025, 04:57:50
Edema of the Arm
Arm edema is the localized swelling of the upper limb due to fluid imbalance between the vascular and interstitial spaces. It may develop gradually or abruptly and can be unilateral or bilateral. Immobility may worsen the condition, while arm elevation and exercise can alleviate it.
Pathophysiology
Fluid accumulates in the arm when the balance of capillary hydrostatic and osmotic pressures, as well as lymphatic drainage, is disrupted. Causes include trauma, burns, envenomation, venous obstruction, surgical or radiation therapy, and systemic vascular syndromes.
Signs and Symptoms
Visible swelling of one or both arms
Pitting or nonpitting edema
Pain, numbness, tingling, or heaviness
Skin changes: erythema, ecchymoses, warmth, or tautness
Reduced range of motion if edema is severe
Possible signs of systemic involvement in envenomation or vascular syndromes
Clinical Assessment
History
Onset, duration, and progression of swelling
Pain, numbness, tingling, or functional limitations
Relation to exercise or arm elevation
Recent trauma, burns, insect or animal bites, IV therapy, surgery, or radiation therapy
Physical Examination
Compare size, symmetry, and girth of both arms (mark reference points for serial measurements)
Assess for pitting, erythema, ecchymoses, and wounds
Palpate radial and brachial pulses, test capillary refill
Evaluate temperature and tenderness
Assess for neurovascular compromise and elevate arm if present
Medical Causes
Cause | Onset/Pattern | Distinguishing Features |
Angioneurotic edema | Acute, recurrent | Sudden, painless, nonpruritic swelling of hands, feet, eyelids, lips, face, neck, genitalia, or viscera; may cause stridor or dyspnea if laryngeal involvement occurs |
Arm trauma | Acute | Severe swelling following crush injuries, fractures, or contusions; may include pain, numbness, paralysis, or ecchymoses |
Burns | Acute | Localized or generalized edema; severity correlates with burn depth; pain and tissue damage present |
Envenomation | Acute | Rapidly spreading edema around bite or sting; erythema, pruritus, paresthesia; systemic symptoms may include nausea, vomiting, hypotension, dyspnea, or seizures |
Superior vena cava syndrome | Gradual | Bilateral arm swelling with facial and neck edema; dilated veins, headache, vertigo, visual disturbances |
Thrombophlebitis | Acute/subacute | Arm swelling with pain, warmth, redness along vein; deep vein thrombosis may cause cyanosis, fever, malaise |
Other causes
Cause | Onset/Pattern | Distinguishing Features |
Surgical treatments | Postoperative | Radical or modified mastectomy, axillary lymph node dissection; disrupts lymphatic drainage causing localized or whole-arm edema |
Radiation therapy | Immediate or delayed | Edema may occur immediately after treatment or months later; commonly follows breast cancer therapy |
IV therapy complications | Acute | Localized infiltration of fluids into interstitial tissue, leading to swelling at the infusion site; may cause tenderness or erythema |
Special Considerations
Elevate the affected arm above heart level to promote fluid drainage
Reposition frequently to prevent pressure ulcers
Apply bandages or dressings as appropriate to encourage circulation
Administer analgesics and anticoagulants as indicated
Monitor for neurovascular compromise and systemic complications
Patient Counseling
Instruct patients on proper postoperative arm care
Teach arm exercises to prevent lymphedema
Advise on early signs of complications, including pain, numbness, or rapidly increasing swelling
Pediatric Pointers
Rare except as part of generalized edema
May occur after trauma, burns, or crush injuries
Monitor fluid balance and neurovascular status closely
Geriatric Pointers
Older adults may be at increased risk due to frailty, reduced mobility, or comorbidities
Exercise caution with interventions that may exacerbate edema
References
Ballots JC, Tamaoki MJ, Atallah AN, Albertoni WM, dos Santos JB, Faloppa F. Treatment of reducible unstable fractures of the distal radius in adults: A randomized controlled trial of De Palma percutaneous pinning versus bridging external fixation. BMC Musculoskelet Disord. 2010;11:137.
Schneppendahl J, Windolf J, Kaufmann RA. Distal radius fractures: Current concepts. J Hand Surg Am. 2012;37:1718–1725.
Rockson SG. Lymphedema. Am J Med. 2001;110:288–295.
Nguyen DH, Suh JD, Wang MB. Upper extremity edema: Evaluation and management. Otolaryngol Clin North Am. 2015;48(6):975–989.
Olszewski WL. Lymphatic drainage disorders: pathophysiology, diagnosis, and therapy. Adv Clin Exp Med. 2014;23(6):911–918.
Cox JL, Tarwater PM. Arm edema: Clinical evaluation and treatment. Am J Med Sci. 2015;350(5):393–401.
