Mwandishi:
Dkt. Sima D, CO
Mhariri:
Dkt. Benjamin L, MD
Acarbose ni dawa inayotumika kushusha sukari kwenye damu kwa wagonjwa wa kisukari aina ya pili. Dawa hii hutumika kuzuia ongezeko la kiwango cha sukari kwenye damu mara baada ya kula. Acarbose hutumika pamoja na mazoezi na lishe sahihi kwa wagonjwa wa kisukari ili kudhibiti ongezeko la sukari kwenye damu.
Upekee wa dawa hii ni kutosababishi kushuka kwa sukari kupita kiasi kama itatumika yenyewe.
Majina ya kibiashara ya acarbose
Acarbose hufahamika kwa majina mengine ya kibiashara kama;
Precose
Miglitol(Glyset)
Voglibose
Glucobay
Glucor
Glumida
Prandase
Fomula ya kikemikali
C25H43NO18
Muonekano
Ni dawa ya kidonge. Umbo na rangi vinaweza kutofautiana kutegemeana na kiwanda kinachozaliza.
Dozi zinazopatikana
Hupatikana kwa vidonge vya:-
Miligramu 25
Miligramu 50
Miligramu 100
Namna ya kutumia
Meza kama utakavyo elekezwa na daktari wako.
Unashauriwa kumeza dakika 30 kabla ya kula chakula.
Namna inavyofanya kazi mwilini
Acarbose ni aina ya oligosaccharide inayofanya kazi ya mashindano kwa kuzuia vimeng’enya vya alpha-glucosidase kuvunja wanga kuwa monosaccharides, kupunguza ufyonzwaji wa kabohaidreti na hivyo kupunguza kiwango cha homon insulin baada ya kula. Acarbose hutakiwa kutumika pamoja na wanga ili iweze kufanya kazi vema, hivyo mtumiaji anapaswa kutumia baada ya kula chakula mara tatu kwa siku.
Umetaboli wa dawa
Dawa hii huchakatwa na mwili ndani ya utumbo mdogo wa chakula
Huanza kufanya kazi baada ya saa 1
Taka mwili ya mabaki ya dawa ya acarbose hutolewa kwenye kinyesi (asilimia 51) na mkojo(asilimia 34)
Wagonjwa wasiopaswa kutumia dawa hii
Wagonjwa walioferi figo
Wagonjwa wenye mzio na dawa ya acarbose
Wagonjwa waliowahi kupata dayabetiki ketoasidosisi
Wagonjwa waliopata tatizo la kuziba utumbo
Wagonjwa wenye vidonda vya tumbo
Wagonjwa wenye figo iliyoferi
Tahadhari wakati wa kutumia dawa ya acarbose
Bado hakuna tafiti za kutosha kuelezea uhusiano wa dawa ya acarbose na hatari zake katika mfumo wa moyo na mishipa ya damu.
Kama ikitumiwa na insulin au sulfonylurea inaweza kushusha sukari kupita kiasi.
Inaweza kushindwa kufanya kazi vizuri kwa wagonjwa wenye maambbukizi au homa, upasuaji mkubwa au majeraha makubwa.
Dawa zenye muingiliano na acarbose
Dawa zisizopaswa kutumika kwa pamoja
Hakuna orodha ya dawa zisizopaswa kutumika kwa pamoja na acarbose
Dawa zenye muingiliano mkali
Dawa zifuatazo hazipaswi kutumika pamoja na acarbose, unawezakutumia mbadala wa dawa ambazo hazina mwingiliano;
Ethanol
Pramlintide
Dawa zenye muingiliano na acarbose ambazo zikitumika pamoja mgonjwa anapaswa kuwa kwenye uchunguzi wa karibu wa daktari;
Albiglutide
Aripiprazole
Asenapine
Atazanavir
Bitter melon
Cinnamon
Ciprofloxacin
Clozapine
Darunavir
Digoxin
Dulaglutide
Exenatide kimiminika cha kuchoma
Exenatide kimiminika cha kuchoma
Fleroxacin
Fosamprenavir
Gemifloxacin
Iloperidone
Indinavir
Insulin aspart
Insulin aspart protamine/insulin aspart
Insulin degludec
Insulin degludec/insulin aspart
Insulin detemir
Insulin glargine
Insulin glulisine
Insulin inhaled
Insulin isophane human/insulin regular human
Insulin lispro
Insulin lispro protamine/insulin lispro
Insulin nph
Insulin regular human
Ketotifen, ya macho
Letermovir
Levofloxacin
Liraglutide
Lopinavir
Lurasidone
Marijuana
Mecasermin
Mipomersen
Moxifloxacin
Nelfinavir
Ofloxacin
Olanzapine
Opuntia ficus indica
Paliperidone
Pancrelipase
Quetiapine
Risperidone
Ritonavir
Saquinavir
Shark cartilage
Somapacitan
Sulfamethoxypyridazine
Tipranavir
Triamcinolone acetonide kimiminika cha kuchoma
Xipamide
Ziprasidone
Dawa zenye muingilian mdogo usio na mashiko
Activated charcoal
Agrimony
American ginseng
Amitriptyline
Amoxapine
Anamu
Bendroflumethiazide
Budesonide
Chlorothiazide
Chlorthalidone
Chromium
Clomipramine
Clonidine
Cornsilk
Cortisone
Cyclopenthiazide
Damiana
Danazol
Deflazacort
Desipramine
Devil's claw
Dexamethasone
Doxepin
Elderberry
Eucalyptus
Fludrocortisone
Fluoxymesterone
Forskolin
Fo-ti
Gotu kola
Guanfacine
Gymnema
Horse chestnut seed
Hydrochlorothiazide
Hydrocortisone
Imipramine
Indapamide
Isoniazid
Juniper
Lofepramine
Lycopus
Maitake
Maprotiline
Mesterolone
Methyclothiazide
Methylprednisolone
Methyltestosterone
Metolazone
Nettle
Nortriptyline
Ofloxacin
Oxandrolone
Oxymetholone
Pegvisomant
Potassium acid phosphate
Potassium chloride
Potassium citrate
Prednisolone
Prednisone
Protriptyline
Sage
Stevia
Testosterone
Testosterone ya kupaka
Testosterone ya kuweka kinywani
Tongkat ali
Trazodone
Trimipramine
Vanadium
Matumizi wakati wa ujauzito
Inaweza kutumiwa kwa mama mjamzito ila hakuna tafiti za kutosha kuhusu mdahara yake.
Matumizi wakati wa kunyonyesha
Epuka kwa kipindi cha kunyonyesha.
Maudhi ya dawa
Maumivu ya tumbo
Tumbo kujaa gesi
Kujamba
Kuharisha
Kuwashwa ngozi
Ongezeko la vimeng'enya vya ini kwenye damu
Huweza kusababisha kuferi kwa ini
Kuvimba
Thrombocytopenia
Pneumatosis cystoides intestinalis
13 Juni 2023 19:18:46
Dawa Acarbose
Imeboreshwa,
25 Septemba 2021 06:46:40
Dawa yoyote ni sumu, usitumie dawa pasipo ushauri wa daktari kuepuka madhara kwenye ogani mbalimbali kama figo na ini. Matumizi ya dawa pasipo ushauri wa daktari unaweza kusababisha madhara na usugu wa vimelea vya maradhi kwenye dawa.
​
ULY CLINIC inakushauri siku zote uwasiliane na daktari wako kwa ushauri na tiba kabla ya kuchukua hatua yoyote ile baad aya kusoma makala hii.
Kupata ushauri zaidi na tiba kutoka kwa daktari wa ULY CLINIC bofya Mawasiliano yetu au Pata tiba.
Rejea za mada hii:
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Bax RP, et al. The pharmacokinetics of meropenem in volunteers. J Antimicrob Chemother. 1989 Sep;24 (Suppl A):311–320.
Burman LA, et al. Pharmacokinetics of meropenem and its metabolite ICI 213,689 in healthy subjects with known renal metabolism of imipenem. J Antimicrob Chemother. 1991 Feb;27(2):219–224.
Christensson BA, et al. Pharmacokinetics of meropenem in subjects with various degrees of renal impairment. Antimicrob Agents Chemother. 1992 Jul;36(7):1532–1537.
DAVIES DF, SHOCK NW. Age changes in glomerular filtration rate, effective renal plasma flow, and tubular excretory capacity in adult males. J Clin Invest. 1950 May;29(5):496–507.
Douglas JG, et al. The pharmacokinetics of cefuroxime in the elderly. J Antimicrob Chemother. 1980 Jul;6(4):543–549.
Granerus G, et al. Reference values for 51Cr-EDTA clearance as a measure of glomerular filtration rate. Scand J Clin Lab Invest. 1981 Oct;41(6):611–616.
Harrison MP, et al. The disposition and metabolism of meropenem in laboratory animals and man. J Antimicrob Chemother. 1989 Sep;24 (Suppl A):265–277.
Jones RN, et al. In-vitro studies of meropenem. J Antimicrob Chemother. 1989 Sep;24 (Suppl A):9–29.
Krutzén E, et al. Plasma clearance of a new contrast agent, iohexol: a method for the assessment of glomerular filtration rate. J Lab Clin Med. 1984 Dec;104(6):955–961.
Ljungberg B, et al. Pharmacokinetics of antimicrobial agents in the elderly. Rev Infect Dis. 1987 Mar-Apr;9(2):250–264.