top of page

Mwandishi:

Dkt. Sima D, CO

Mhariri:

Dkt. Benjamin L, MD

kirusi mumps-ulyclinic

Acarbose ni dawa inayotumika kushusha sukari kwenye damu kwa wagonjwa wa kisukari aina ya pili. Dawa hii hutumika kuzuia ongezeko la kiwango cha sukari kwenye damu mara baada ya kula. Acarbose hutumika pamoja na mazoezi na lishe sahihi kwa wagonjwa wa kisukari ili kudhibiti ongezeko la sukari kwenye damu.


Upekee wa dawa hii ni kutosababishi kushuka kwa sukari kupita kiasi kama itatumika yenyewe.


Majina ya kibiashara ya acarbose

Acarbose hufahamika kwa majina mengine ya kibiashara kama;

  • Precose

  • Miglitol(Glyset)

  • Voglibose

  • Glucobay

  • Glucor

  • Glumida

  • Prandase


Fomula ya kikemikali

C25H43NO18


Muonekano

Ni dawa ya kidonge. Umbo na rangi vinaweza kutofautiana kutegemeana na kiwanda kinachozaliza.


Dozi zinazopatikana

Hupatikana kwa vidonge vya:-

  • Miligramu 25

  • Miligramu 50

  • Miligramu 100


Namna ya kutumia

  • Meza kama utakavyo elekezwa na daktari wako.

  • Unashauriwa kumeza dakika 30 kabla ya kula chakula.


Namna inavyofanya kazi mwilini

Acarbose ni aina ya oligosaccharide inayofanya kazi ya mashindano kwa kuzuia vimeng’enya vya alpha-glucosidase kuvunja wanga kuwa monosaccharides, kupunguza ufyonzwaji wa kabohaidreti na hivyo kupunguza kiwango cha homon insulin baada ya kula. Acarbose hutakiwa kutumika pamoja na wanga ili iweze kufanya kazi vema, hivyo mtumiaji anapaswa kutumia baada ya kula chakula mara tatu kwa siku.


Umetaboli wa dawa

  • Dawa hii huchakatwa na mwili ndani ya utumbo mdogo wa chakula

  • Huanza kufanya kazi baada ya saa 1

  • Taka mwili ya mabaki ya dawa ya acarbose hutolewa kwenye kinyesi (asilimia 51) na mkojo(asilimia 34)


Wagonjwa wasiopaswa kutumia dawa hii

  • Wagonjwa walioferi figo

  • Wagonjwa wenye mzio na dawa ya acarbose

  • Wagonjwa waliowahi kupata dayabetiki ketoasidosisi

  • Wagonjwa waliopata tatizo la kuziba utumbo

  • Wagonjwa wenye vidonda vya tumbo

  • Wagonjwa wenye figo iliyoferi


Tahadhari wakati wa kutumia dawa ya acarbose

  • Bado hakuna tafiti za kutosha kuelezea uhusiano wa dawa ya acarbose na hatari zake katika mfumo wa moyo na mishipa ya damu.

  • Kama ikitumiwa na insulin au sulfonylurea inaweza kushusha sukari kupita kiasi.

  • Inaweza kushindwa kufanya kazi vizuri kwa wagonjwa wenye maambbukizi au homa, upasuaji mkubwa au majeraha makubwa.


Dawa zenye muingiliano na acarbose

Dawa zisizopaswa kutumika kwa pamoja


Hakuna orodha ya dawa zisizopaswa kutumika kwa pamoja na acarbose


Dawa zenye muingiliano mkali


Dawa zifuatazo hazipaswi kutumika pamoja na acarbose, unawezakutumia mbadala wa dawa ambazo hazina mwingiliano;


  • Ethanol

  • Pramlintide


Dawa zenye muingiliano na acarbose ambazo zikitumika pamoja mgonjwa anapaswa kuwa kwenye uchunguzi wa karibu wa daktari;


  • Albiglutide

  • Aripiprazole

  • Asenapine

  • Atazanavir

  • Bitter melon

  • Cinnamon

  • Ciprofloxacin

  • Clozapine

  • Darunavir

  • Digoxin

  • Dulaglutide

  • Exenatide kimiminika cha kuchoma

  • Exenatide kimiminika cha kuchoma

  • Fleroxacin

  • Fosamprenavir

  • Gemifloxacin

  • Iloperidone

  • Indinavir

  • Insulin aspart

  • Insulin aspart protamine/insulin aspart

  • Insulin degludec

  • Insulin degludec/insulin aspart

  • Insulin detemir

  • Insulin glargine

  • Insulin glulisine

  • Insulin inhaled

  • Insulin isophane human/insulin regular human

  • Insulin lispro

  • Insulin lispro protamine/insulin lispro

  • Insulin nph

  • Insulin regular human

  • Ketotifen, ya macho

  • Letermovir

  • Levofloxacin

  • Liraglutide

  • Lopinavir

  • Lurasidone

  • Marijuana

  • Mecasermin

  • Mipomersen

  • Moxifloxacin

  • Nelfinavir

  • Ofloxacin

  • Olanzapine

  • Opuntia ficus indica

  • Paliperidone

  • Pancrelipase

  • Quetiapine

  • Risperidone

  • Ritonavir

  • Saquinavir

  • Shark cartilage

  • Somapacitan

  • Sulfamethoxypyridazine

  • Tipranavir

  • Triamcinolone acetonide kimiminika cha kuchoma

  • Xipamide

  • Ziprasidone


Dawa zenye muingilian mdogo usio na mashiko


  • Activated charcoal

  • Agrimony

  • American ginseng

  • Amitriptyline

  • Amoxapine

  • Anamu

  • Bendroflumethiazide

  • Budesonide

  • Chlorothiazide

  • Chlorthalidone

  • Chromium

  • Clomipramine

  • Clonidine

  • Cornsilk

  • Cortisone

  • Cyclopenthiazide

  • Damiana

  • Danazol

  • Deflazacort

  • Desipramine

  • Devil's claw

  • Dexamethasone

  • Doxepin

  • Elderberry

  • Eucalyptus

  • Fludrocortisone

  • Fluoxymesterone

  • Forskolin

  • Fo-ti

  • Gotu kola

  • Guanfacine

  • Gymnema

  • Horse chestnut seed

  • Hydrochlorothiazide

  • Hydrocortisone

  • Imipramine

  • Indapamide

  • Isoniazid

  • Juniper

  • Lofepramine

  • Lycopus

  • Maitake

  • Maprotiline

  • Mesterolone

  • Methyclothiazide

  • Methylprednisolone

  • Methyltestosterone

  • Metolazone

  • Nettle

  • Nortriptyline

  • Ofloxacin

  • Oxandrolone

  • Oxymetholone

  • Pegvisomant

  • Potassium acid phosphate

  • Potassium chloride

  • Potassium citrate

  • Prednisolone

  • Prednisone

  • Protriptyline

  • Sage

  • Stevia

  • Testosterone

  • Testosterone ya kupaka

  • Testosterone ya kuweka kinywani

  • Tongkat ali

  • Trazodone

  • Trimipramine

  • Vanadium


Matumizi wakati wa ujauzito

Inaweza kutumiwa kwa mama mjamzito ila hakuna tafiti za kutosha kuhusu mdahara yake.


Matumizi wakati wa kunyonyesha

Epuka kwa kipindi cha kunyonyesha.


Maudhi ya dawa

  • Maumivu ya tumbo

  • Tumbo kujaa gesi

  • Kujamba

  • Kuharisha

  • Kuwashwa ngozi

  • Ongezeko la vimeng'enya vya ini kwenye damu

  • Huweza kusababisha kuferi kwa ini

  • Kuvimba

  • Thrombocytopenia

  • Pneumatosis cystoides intestinalis


13 Juni 2023 19:18:46

Dawa Acarbose

Imeboreshwa,

25 Septemba 2021 06:46:40

Dawa yoyote ni sumu, usitumie dawa pasipo ushauri wa daktari kuepuka madhara kwenye ogani mbalimbali kama figo na ini. Matumizi ya dawa pasipo ushauri wa daktari unaweza kusababisha madhara na usugu wa vimelea vya maradhi kwenye dawa.

ULY CLINIC inakushauri siku zote uwasiliane na daktari wako kwa ushauri na tiba kabla ya kuchukua hatua yoyote ile baad aya kusoma makala hii.

Kupata ushauri zaidi na tiba kutoka kwa daktari wa ULY CLINIC bofya Mawasiliano yetu au Pata tiba.

Rejea za mada hii:

  1. Bäck SE, et al. Age dependence of renal function: clearance of iohexol and p-amino hippurate in healthy males. Scand J Clin Lab Invest. 1989 Nov;49(7):641–646.

  2. Bax RP, et al. The pharmacokinetics of meropenem in volunteers. J Antimicrob Chemother. 1989 Sep;24 (Suppl A):311–320.

  3. Burman LA, et al. Pharmacokinetics of meropenem and its metabolite ICI 213,689 in healthy subjects with known renal metabolism of imipenem. J Antimicrob Chemother. 1991 Feb;27(2):219–224.

  4. Christensson BA, et al. Pharmacokinetics of meropenem in subjects with various degrees of renal impairment. Antimicrob Agents Chemother. 1992 Jul;36(7):1532–1537. 

  5. DAVIES DF, SHOCK NW. Age changes in glomerular filtration rate, effective renal plasma flow, and tubular excretory capacity in adult males. J Clin Invest. 1950 May;29(5):496–507.

  6. Douglas JG, et al. The pharmacokinetics of cefuroxime in the elderly. J Antimicrob Chemother. 1980 Jul;6(4):543–549.

  7. Granerus G, et al. Reference values for 51Cr-EDTA clearance as a measure of glomerular filtration rate. Scand J Clin Lab Invest. 1981 Oct;41(6):611–616.

  8. Harrison MP, et al. The disposition and metabolism of meropenem in laboratory animals and man. J Antimicrob Chemother. 1989 Sep;24 (Suppl A):265–277. 

  9. Jones RN, et al. In-vitro studies of meropenem. J Antimicrob Chemother. 1989 Sep;24 (Suppl A):9–29. 

  10. Krutzén E, et al. Plasma clearance of a new contrast agent, iohexol: a method for the assessment of glomerular filtration rate. J Lab Clin Med. 1984 Dec;104(6):955–961.

  11. Ljungberg B, et al. Pharmacokinetics of antimicrobial agents in the elderly. Rev Infect Dis. 1987 Mar-Apr;9(2):250–264.

bottom of page