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© Hairuhusiwi kukopi bila kibali cha ULYCLINIC

Nephritic syndrome


Are those which cause glomerular to leak blood or protein into urine. Glomerular disease may be a result of a primary condition of the kidney, or may be secondary to a systemic disorder.

Risk factors

Signs and Symptoms

Diagnostic criteria

• Proteinuria
• Reduced GFR (and its effects)
• Haematuria
• Hypertension
• Oedema.


• Renal function test
• Urinalysis
• Urine culture
• Complete blood count
• Others on tertiary hospital e.g. lupus serology, complements


  • Pharmacological


    Fluid overload

    • Furosemide I.V bolus, 80 mg.

    If hypertension

    If diastolic blood pressure is greater than 100 mmHg or systolic blood pressure is above 150 mmHg:
    • Amlodipine 5 mg (PO) as a single dose

    Note: The definitive treatment of nephritis depends on the cause – an assumption of acute post streptococcal nephritis or any other disease cannot be made without specific investigation which may include renal biopsy.
  • Non-pharmacological

    • Give oxygen, and nurse in semi-Fowlers position if patient has respiratory distress.
    • Restrict intake of all salt
    • Restrict potassium containing foods and fluids
    • Restrict fluid intake to 10 mL/kg/day daily plus visible fluid losses


Updated on,

23 Novemba 2020 11:53:17


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