Triggers of thyroid storm include:

• Acute infections
• Thyroidal or nonthyroidal surgeries
• Iodinated contrast dyes

External beam radiation therapy. It should be considered in very sick patients if they present with recent history of thyrotoxicosis and a recent history of precipitating factor.

Patients with thyroid storm (tachycardia, arrhythmias, congestive heart failure, hypotension, hyperpyrexia, agitation, delirium, psychosis, stupor and coma, as well as nausea, vomiting, diarrhoea, and hepatic failure) should receive a multimodal treatment including:

• Beta-adrenergic blockade
• Antithyroid medicine therapy
• Inorganic iodide
• Corticosteroid therapy
• Aggressive cooling with acetaminophen and cooling blankets
• Volume resuscitation
• Respiratory support
• Monitoring in an intensive care unit.

Thyroid storm is not a matter of thyroid levels increased beyond those of uncomplicated thyrotoxicosis, but the systemic decompensation that occurs.