Stevens Johnson Syndrome (SJS)

Introduction

It is a rare but serious problem most often caused by reaction to medicines. It causes the skin to blister and peel off.

Signs & symptoms

• Abrupt development of erythema multiform
• Patients almost invariably have a prodromal with fever, malaise, and arthralgia’s
• Erosions, hemorrhage and crusts on lips, and erosions in mouth covered by necrotic white pseudo membrane
• Involvement of the eyes in 70–90% of cases: Erosive conjunctivitis, can lead to scarring
• Involvement of genitalia in 60–70% of cases, with painful erosions

Diagnostic criteria

• Abrupt development of erythema multiform
• Patients almost invariably have a prodromal with fever, malaise, and arthralgia’s
• Erosions, hemorrhage and crusts on lips, and erosions in mouth covered by necrotic white pseudo membrane
• Involvement of the eyes in 70–90% of cases: Erosive conjunctivitis, can lead to scarring
• Involvement of genitalia in 60–70% of cases, with painful erosions