Stevens Johnson Syndrome (SJS)
Introduction
It is a rare but serious problem most often caused by reaction to medicines. It causes the skin to blister and peel off.
Signs & symptoms
• Abrupt development of erythema multiform
• Patients almost invariably have a prodromal with fever, malaise, and arthralgia’s
• Erosions, hemorrhage and crusts on lips, and erosions in mouth covered by necrotic white pseudo membrane
• Involvement of the eyes in 70–90% of cases: Erosive conjunctivitis, can lead to scarring
• Involvement of genitalia in 60–70% of cases, with painful erosions
Diagnostic criteria
• Abrupt development of erythema multiform
• Patients almost invariably have a prodromal with fever, malaise, and arthralgia’s
• Erosions, hemorrhage and crusts on lips, and erosions in mouth covered by necrotic white pseudo membrane
• Involvement of the eyes in 70–90% of cases: Erosive conjunctivitis, can lead to scarring
• Involvement of genitalia in 60–70% of cases, with painful erosions
Investigation
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Treatment
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Non-Pharmacological treatment
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Pharmacological
- • Admission,
• Close monitoring (fluids, Nutrition and electrolytes)
• Topical disinfection
• Prompt treatment of secondary infection.
Note: Systemic corticosteroids, if employed should be early, later in the course they increase the risk of infection and slow healing
Prevention
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Updated on,
3 Novemba 2020 12:38:00
References
- 1.STG