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Mwandishi:

Dkt. Sospeter M, MD

Mhariri:

Dkt. Lugonda B, MD

4 Juni 2022 20:56:39

Dawa clarithromycin

Dawa clarithromycin

Clarithromycin ni dawa ya antibayotiki kundi la macrolide inayotumika sana kutibu magonjwa mbalimbali kutokana na maambukizi ya bakteria wanaodhuriwa na dawa hii.


Majina mengine ya clarithromycin


Clarithromycin hufahamika kwa majina ya kibiashara kama:

  • Biaxin

  • Biaxin XL


Uzito na fomu ya clarithromycin


Clarithromycin hupatikana kama, kimiminika kwa ajili ya kunywa na kama kidonge.


Kimiminika huwa na uzito ufuatao:


  • 125/5ml

  • 250mg/5ml


Kidonge huwa na uzito ufuatao:

  • 250mg

  • 500mg


Dawa kundi moja na clarithromycin


Dawa zingine zilizo kundi moja na clarithromycin ni zile ambazo huwa kundi macrolide ni kama vile:


  • Erythromycin

  • Roxithromycin

  • Azithromycin

Vimelea wanaodhuriwa na clarithromycin


Vimelea wanaodhuliwa/kuuliwa na clarithromycin ni pamoja na:


  • Haemophilus influenza

  • Streptococcus pneumonia

  • Streptococcus pyogenes

  • Streptococcus agalactiae

  • Moraxella catarrhalis

  • Neisseria gonorrhoeae

  • H. Pylori

  • Campylobacter spp

  • Bacteroides melaninogenicus

  • Chlamydia pneumonia

  • Chlamydia trachomatis

  • Mycobacterium chelonae

  • Mycobacterium leprae

  • Mycobacterium marinum

  • Mycobacterium avium complex

  • Legionella spp.


Clarithromycin hutibu nini?:


Clarithromycin hutibu magonjwa yafuatayo yanayosababishwa na bakteria wanaodhuriwa na dawa hii:


  • Brokaitizi kali iliyoamka

  • Sinuzaitizi katika fupa maxilla

  • Maambukizi ya bakteria wa TB na ukoma

  • Ukoma

  • Maambukizi ya bartenolla

  • Ugonjwa wa Lyme

  • Vidonda vya tumbo kutokana na maambukizi ya H.pylori

  • Maambukizi kwenye tonses na koo

  • Nimonia ya jamii

  • Maambukizi kwenye ngozi

  • Dondakoo

  • Maambukizi kwenye kuta za ndani ya moyo

  • Homa ya ubongo kutokana na Toxoplasma gondii

  • Ugonjwa wa cryptosporidiosis


Namna clarithromycin inavyofanya kazi


Clarithromycin hufanya kazi kwa kuzuia uzalishaji wa protini muhimu za ujenzi wa bakteria wanaodhurika na dawa hii na hivyo kufanya kutoendelea kuzaliana kwa bakteria.


Wagonjwa wasiopaswa kutumia clarithromycin


Clarithromycin haipaswi kutumika kwa wagonjwa wenye mzio na clarithromycin.

Tahadhari inapaswa kuchukuliwa kwa wagonjwa wenye matatizo ya figo na wale wenye historia ya manjano baada ya kutumia dawa hii.


Matumizi ya clarithromycin na pombe


Clarithromycin huwa haina mwingiliano na pombe, unaweza kutumia clarithromycin na pombe, hata hivyo usitumie kiasi kikubwa cha pombe ili kuepuka maudhi ya kichefuchefu na kutapika. Pombe kwa ujumla huwa haishauriwi kutumika wakati wa kunywa dawa kutokana na kuweza kupunguza nguvu mwilini na kufanya uchelewe kupona kupona.


Ufyonzwaji wa clarithromycin


Mara baada ya kunywa dawa asilimia 50 tu ya dawa hufyonzwa na kuingia kwenye damu kwa ajili ya kufanyakazi yake.


Matumizi ya clarithromycin na chakula


Chakula huchelewesha ufyonzaji licha ya kutoathiri kiwango cha dawa kinachofyonzwa


Utoaji taka mwilini


Asilimia 30 hadi 55 ya dawa hutolewa kwa njia ya mkojo.


Nusu maisha ya clarithromycin


Clarithromycin mara baada ya kuingia kwenye damu, hudumu kwa muda wa saa 3 hadi 9 kabla ya kutolewa nje ya mwili.


Matumizi ya clarithromycin kwa mama mjamzito


Hakuna taarifa za kutoshaza kutolea maamuzi kuhusu madhara ya dawa hii kwenye ujauzito. Hata hivyo haishauriwi kutumika kwa mjamzito.na kama itatumika, faida zinapaswa kuwa kubwa kuliko madhara yanayoweza kujitokeza.


Matumizi ya clarithromycin kwa mama anayenyonyesha


Kiasi kidogo cha dawa huingia kwenye maziwa ya mama na hivyo kusababisha maudhi kidogo kama kuharisha, kukosa hamu ya kula na sononeko. Unapofanya uamuzi wa kutumia dawa hii, faida zinapaswa kuwa kubwa kuliko madhara yanayoweza kujitokeza kwa mtoto.


Maudhi ya clarithromycin


Maudhi yanayotokea sana


  • Kichefuchefu

  • Kutapika

  • Kuhara

  • Kubadilika kwa ladha ya chakula

  • Kupanda kwa kiwango cha BUN

  • Harara kwenye ngozi

  • Kiungulia

  • Maumivu chembe ya moyo

  • Maumvu ya kichwa

  • Ongezeko la muda wa kupanda prothrombin


Maudhi ya nadra


  • Mzio wa anafailaksia

  • Kukosa hamu ya kula

  • Wago uliopitiliza

  • Kizunguzungu

  • Gesi tumboni

  • Ongezeko la kiwango cha vimeng’enya vya ini

  • Kuhisi vitu ambavyo havipo

  • Kushuka kwa sukari mwilini

  • Kuumia kwa ini

  • ongezek

  • ongezeko la creatinine kwenye damu

  • Upungufu wa chembe nyeupe za damu

  • Kuumia kwa kongosho

  • Saikosis

  • Tabia za kupaniki

  • Degedege

  • Manjano

  • Sindromu ya Stevens-Johnson

  • Upungufu wa chembe sahani za damu


Je endapo utasahau dozi ya clarithromycin ufanyaje ?


Kama umesahau kutumia dozi yako, tumia mara utakapokumbuka isipokuwa endapo muda wa kunyw adozi nyingine umefika ambapo utapaswa kusubilia muda ufike ndipo utumie dozi hiyo na kuendelea kama ulivyoshauriwa na daktari wako. Usitumie dozi mbili kwa wakati mmoja.


Uhifadhi ya clarithromycin


Hifadhi dawa yako katika joto la ndani ya nyumba kati ya nyuzi za selishaz 20 hadi 30. Usiweke kwenye friji au sehemu yenye mwanga wa jua au joto ili kuepuka kuharibu dawa.


Dawa zisizopaswa kutumika na clarithromycin


Dawa zifuatazo hazipawi kutumika pamoja na clarithromycin kwa kuwa husababisha madhara makubwa:


  • Alfuzosin

  • Chloroquine

  • Cisapride

  • Clofazimine

  • Cobimetinib

  • Conivaptan

  • Dihydroergotamine

  • Dihydroergotamine intranasal

  • Dofetilide

  • Eliglustat

  • Ergoloid mesylates

  • Ergonovine

  • Ergotamine

  • Finerenone

  • Flibanserin

  • Ibutilide

  • Indapamide

  • Ivabradine

  • Lomitapide

  • Lonafarnib

  • Lovastatin

  • Lurasidone

  • Mavacamten

  • Methylergonovine

  • Naloxegol

  • Pacritinib

  • Pentamidine

  • Pimozide

  • Quinidine

  • Regorafenib

  • Rifabutin

  • Saquinavir

  • Simvastatin

  • Venetoclax

  • Voclosporin


Dawa zenye mwingiliano mkali na clarithromycin


Dawa zifuatazo zina mwingiliano mkali na clarithromycin kiasi cha kutopaswa tumika pamoja:


  • Abametapir

  • Acalabrutinib

  • Ado-trastuzumab emtansine

  • Afatinib

  • Almotriptan

  • Alprazolam

  • Amiodarone

  • Amisulpride

  • Amitriptyline

  • Amoxapine

  • Anagrelide

  • Antithrombin alfa

  • Antithrombin iii

  • Apalutamide

  • Apomorphine

  • Aprepitant

  • Argatroban

  • Aripiprazole

  • Arsenic trioxide

  • Artemether

  • Artemether/lumefantrine

  • Asenapine

  • Atomoxetine

  • Atorvastatin

  • Avanafil

  • Avapritinib

  • Axitinib

  • Bazedoxifene/conjugated estrogens

  • Bcg vaccine live

  • Bedaquiline

  • Bemiparin

  • Bivalirudin

  • Bosutinib

  • Brigatinib

  • Bromocriptine

  • Budesonide

  • Buprenorphine

  • Buprenorphine transdermal

  • Buspirone

  • Cabazitaxel

  • Cabergoline

  • Cabozantinib

  • Calcitriol

  • Carbamazepine

  • Ceritinib

  • Chloroquine

  • Chlorpromazine

  • Cholera vaccine

  • Cilostazol

  • Cinacalcet

  • Ciprofloxacin

  • Citalopram

  • Clomipramine

  • Clopidogrel

  • Clozapine

  • Cobicistat

  • Colchicine

  • Conjugated estrogens

  • Conjugated estrogens, vaginal

  • Copanlisib

  • Cortisone

  • Crizotinib

  • Cyclosporine

  • Dabrafenib

  • Dalteparin

  • Daridorexant

  • Darifenacin

  • Dasatinib

  • Degarelix

  • Desflurane

  • Desipramine

  • Deutetrabenazine

  • Dexamethasone

  • Diazepam

  • Digoxin

  • Disopyramide

  • Dofetilide

  • Donepezil

  • Doxepin

  • Dronedarone

  • Droperidol

  • Edoxaban

  • Efavirenz

  • Elbasvir/grazoprevir

  • Eletriptan

  • Eliglustat

  • Eluxadoline

  • Elvitegravir/cobicistat/emtricitabine/tenofovir df

  • Encorafenib

  • Enoxaparin

  • Entrectinib

  • Enzalutamide

  • Epinephrine

  • Epinephrine racemic

  • Erdafitinib

  • Ergoloid mesylates

  • Ergotamine

  • Eribulin

  • Erlotinib

  • Erythromycin base

  • Erythromycin ethylsuccinate

  • Erythromycin lactobionate

  • Erythromycin stearate

  • Escitalopram

  • Estradiol

  • Estrogens conjugated synthetic

  • Estropipate

  • Etonogestrel

  • Etravirine

  • Everolimus

  • Fedratinib

  • Felbamate

  • Fentanyl

  • Fentanyl intranasal

  • Fentanyl transdermal

  • Fentanyl transmucosal

  • Fesoterodine

  • Fexinidazole

  • Fingolimod

  • Fluconazole

  • Fludrocortisone

  • Fluphenazine

  • Fluticasone intranasal

  • Fluvastatin

  • Fondaparinux

  • Formoterol

  • Fosamprenavir

  • Fostemsavir

  • Gadobenate

  • Gemifloxacin

  • Gilteritinib

  • Glasdegib

  • Granisetron

  • Haloperidol

  • Heparin

  • Hydrocortisone

  • Hydroxychloroquine sulfate

  • Hydroxyprogesterone caproate

  • Ibrutinib

  • Idelalisib

  • Imipramine

  • Indinavir

  • Infigratinib

  • Inotuzumab

  • Irinotecan

  • Irinotecan liposomal

  • Isoflurane

  • Isradipine

  • Itraconazole

  • Ivosidenib

  • Ixabepilone

  • Ketamine

  • Ketoconazole

  • Lapatinib

  • Larotrectinib

  • Lefamulin

  • Lemborexant

  • Levoketoconazole

  • Lithium

  • Lofepramine

  • Lofexidine

  • Loperamide

  • Lopinavir

  • Loratadine

  • Lorlatinib

  • Lumacaftor/ivacaftor

  • Lumefantrine

  • Lurbinectedin

  • Macimorelin

  • Macitentan

  • Maprotiline

  • Mefloquine

  • Mestranol

  • Methadone

  • Methylergonovine

  • Methylprednisolone

  • Midazolam

  • Midazolam intranasal

  • Midostaurin

  • Mifepristone

  • Mirtazapine

  • Mobocertinib

  • Modafinil

  • Moxifloxacin

  • Nefazodone

  • Nelfinavir

  • Neratinib

  • Nevirapine

  • Nilotinib

  • Nortriptyline

  • Octreotide

  • Octreotide (antidote)

  • Olanzapine

  • Olaparib

  • Ombitasvir/paritaprevir/ritonavir

  • Ombitasvir/paritaprevir/ritonavir & dasabuvir (dsc)

  • Ondansetron

  • Osimertinib

  • Oxaliplatin

  • Oxycodone

  • Palbociclib

  • Panobinostat

  • Pazopanib

  • Pemigatinib

  • Perphenazine

  • Pexidartinib

  • Phenindione

  • Pimavanserin

  • Pitolisant

  • Pomalidomide

  • Ponatinib

  • Ponesimod

  • Pralsetinib

  • Prednisone

  • Primaquine

  • Procainamide

  • Prochlorperazine

  • Progesterone intravaginal gel

  • Progesterone micronized

  • Progesterone, natural

  • Promazine

  • Promethazine

  • Propafenone

  • Protamine

  • Protriptyline

  • Quetiapine

  • Quinidine

  • Quinupristin/dalfopristin

  • Ranolazine

  • Repaglinide

  • Ribociclib

  • Rifabutin

  • Rimegepant

  • Ritonavir

  • Rivaroxaban

  • Romidepsin

  • Rosuvastatin

  • Ruxolitinib

  • Ruxolitinib topical

  • Saquinavir

  • Selpercatinib

  • Selumetinib

  • Sertraline

  • Sevoflurane

  • Sildenafil

  • Silodosin

  • Siponimod

  • Sirolimus

  • Solifenacin

  • Sonidegib

  • Sorafenib

  • Sotalol

  • Stiripentol

  • Sunitinib

  • Suvorexant

  • Tacrolimus

  • Tadalafil

  • Talazoparib

  • Tamsulosin

  • Tazemetostat

  • Temsirolimus

  • Teniposide

  • Tepotinib

  • Tetrabenazine

  • Theophylline

  • Thioridazine

  • Tiagabine

  • Tipranavir

  • Tofacitinib

  • Tolterodine

  • Tolvaptan

  • Topotecan

  • Toremifene

  • Trabectedin

  • Trazodone

  • Triamcinolone acetonide injectable suspension

  • Triazolam

  • Triclabendazole

  • Trifluoperazine

  • Trimipramine

  • Tucatinib

  • Typhoid vaccine live

  • Ubrogepant

  • Umeclidinium bromide/vilanterol inhaled

  • Vandetanib

  • Vardenafil

  • Vemurafenib

  • Venetoclax

  • Venlafaxine

  • Vilanterol/fluticasone furoate inhaled

  • Vilazodone

  • Vorapaxar

  • Voriconazole

  • Vorinostat

  • Voxelotor

  • Voxilaprevir

  • Zanubrutinib

  • Ziprasidone


Dawa zenye mwingiliano wa wastani na clarithromycin


Dawa zifuatazo endapo zitatumika pamoja na clarithromycin, mgonjwa anapaswa kuwa kwenye uangalizi wa karibu wa mtaalamu wa afya:


  • Abemaciclib

  • Albuterol

  • Alfentanil

  • Alfuzosin

  • Alosetron

  • Amikacin

  • Amitriptyline

  • Amlodipine

  • Apalutamide

  • Arformoterol

  • Armodafinil

  • Atazanavir

  • Atogepant

  • Azithromycin

  • Balsalazide

  • Bazedoxifene/conjugated estrogens

  • Bedaquiline

  • Belzutifan

  • Benzhydrocodone/acetaminophen

  • Berotralstat

  • Betrixaban

  • Bexarotene

  • Biotin

  • Bortezomib

  • Bosentan

  • Brentuximab vedotin

  • Brexpiprazole

  • Bromocriptine

  • Budesonide

  • Buprenorphine

  • Buprenorphine

  • Calcifediol

  • Cannabidiol

  • Capmatinib

  • Cariprazine

  • Cefdinir

  • Cefditoren

  • Cefoxitin

  • Cefpodoxime

  • Cefuroxime

  • Cenobamate

  • Ceritinib

  • Cevimeline

  • Chlordiazepoxide

  • Chlorpropamide

  • Cholic acid

  • Ciclesonide

  • Cimetidine

  • Clevidipine

  • Clonazepam

  • Clorazepate

  • Conjugated estrogens

  • Conjugated estrogens

  • Cortisone

  • Crizotinib

  • Crofelemer

  • Cyclosporine

  • Dabigatran

  • Dabrafenib

  • Dapsone

  • Darolutamide

  • Darunavir

  • Dasatinib

  • Daunorubicin

  • Deferasirox

  • Deflazacort

  • Dexamethasone

  • Diazepam

  • Dienogest/estradiol valerate

  • Digoxin

  • Diltiazem

  • Disopyramide

  • Docetaxel

  • Dolasetron

  • Donepezil

  • Doravirine

  • Doxepin cream

  • Doxorubicin

  • Doxorubicin liposomal

  • Dronabinol

  • Dutasteride

  • Duvelisib

  • Efavirenz

  • Elagolix

  • Elvitegravir

  • Elvitegravir/cobicistat/emtricitabine/tenofovir df

  • Encorafenib

  • Enfortumab vedotin

  • Enzalutamide

  • Eplerenone

  • Erlotinib

  • Erythromycin base

  • Erythromycin ethylsuccinate

  • Erythromycin lactobionate

  • Erythromycin stearate

  • Estradiol

  • Estrogens conjugated synthetic

  • Estrogens esterified

  • Estropipate

  • Eszopiclone

  • Ethinylestradiol

  • Etoposide

  • Eucalyptus

  • Ezogabine

  • Fedratinib

  • Felodipine

  • Finasteride

  • Flecainide

  • Fludrocortisone

  • Fluoxetine

  • Flurazepam

  • Fluticasone furoate

  • Fluvoxamine

  • Foscarnet

  • Fostamatinib

  • Galantamine

  • Gefitinib

  • Gemtuzumab

  • Gentamicin

  • Glecaprevir/pibrentasvir

  • Glimepiride

  • Glipizide

  • Glyburide

  • Goserelin

  • Guanfacine

  • Histrelin

  • Hydrocodone

  • Hydrocortisone

  • Hydroxyzine

  • Ifosfamide

  • Iloperidone

  • Imatinib

  • Indacaterol

  • Indinavir

  • Isoniazid

  • Isradipine

  • Istradefylline

  • Itraconazole

  • Ivacaftor

  • Ivermectin

  • Ketoconazole

  • Lacosamide

  • Lansoprazole

  • Lapatinib

  • Lenvatinib

  • Letermovir

  • Leuprolide

  • Levalbuterol

  • Levamlodipine

  • Levofloxacin

  • Levoketoconazole

  • Levomilnacipran

  • Levonorgestrel /ethinylestradiol/ferrous bisglycinate

  • Loperamide

  • Lumacaftor/ivacaftor

  • Lumateperone

  • Maraviroc

  • Marijuana

  • Medroxyprogesterone

  • Mestranol

  • Methadone

  • Methylprednisolone

  • Mifepristone

  • Mitotane

  • Mometasone

  • Montelukast

  • Naldemedine

  • Nateglinide

  • Nelfinavir

  • Neomycin po

  • Netupitant/palonosetron

  • Nicardipine

  • Nifedipine

  • Nilotinib

  • Nimodipine

  • Nintedanib

  • Nirmatrelvir

  • Nirmatrelvir/ritonavir

  • Nisoldipine

  • Nitrendipine

  • Ofloxacin

  • Oliceridine

  • Olodaterol

  • Osilodrostat

  • Osimertinib

  • Ospemifene

  • Oxaliplatin

  • Oxybutynin

  • Ozanimod

  • Paclitaxel

  • Paliperidone

  • Panobinostat

  • Pantothenic acid

  • Parecoxib

  • Paricalcitol

  • Paromomycin

  • Paroxetine

  • Pasireotide

  • Pazopanib

  • Perampanel

  • Pimozide

  • Pioglitazone

  • Piperacillin

  • Pitavastatin

  • Polatuzumab vedotin

  • Posaconazole

  • Pravastatin

  • Praziquantel

  • Prednisolone

  • Prednisone

  • Propafenone

  • Pyridoxine

  • Pyridoxine (kiuaji sumu)

  • Quazepam

  • Quetiapine

  • Quinine

  • Rabeprazole

  • Ranolazine

  • Rifabutin

  • Rifampin

  • Rifaximin

  • Rilpivirine

  • Riociguat

  • Ripretinib

  • Risperidone

  • Ritonavir

  • Romidepsin

  • Rosiglitazone

  • Rucaparib

  • Sacubitril/valsartan

  • Salmeterol

  • Saquinavir

  • Saxagliptin

  • Selpercatinib

  • Silodosin

  • Sirolimus

  • Sodium picosulfate/magnesium oxide/anhydrous citric acid

  • Sofosbuvir/velpatasvir

  • Sorafenib

  • St john's wort

  • Stiripentol

  • Streptomycin

  • Sufentanil

  • Sufentanil sl

  • Sulfamethoxazole

  • Tacrolimus

  • Tacrolimus ointment

  • Tamoxifen

  • Tasimelteon

  • Tazemetostat

  • Tecovirimat

  • Telavancin

  • Teniposide

  • Terbinafine

  • Tezacaftor

  • Thiamine

  • Ticagrelor

  • Tinidazole

  • Tisotumab vedotin

  • Tobramycin

  • Tolazamide

  • Tolbutamide

  • Tolvaptan

  • Tramadol

  • Trimethoprim

  • Trimipramine

  • Triptorelin

  • Tropisetron

  • Ulipristal

  • Umeclidinium bromide/vilanterol inhaled

  • Upadacitinib

  • Valbenazine

  • Valsartan

  • Velpatasvir

  • Venlafaxine

  • Verapamil

  • Vilanterol/fluticasone furoate inhaled

  • Vinblastine

  • Vincristine

  • Vincristine liposomal

  • Vinorelbine

  • Voclosporin

  • Voriconazole

  • Warfarin

  • Zidovudine

  • Ziprasidone

  • Zonisamide


Dawa zenye mwingilino mdogo na clarithromycine


Dawa zifuatazo huwa na mwingiliano mdogo sana na clarithromycin


  • Aliskiren

  • Alvimopan

  • Ambrisentan

  • Amobarbital

  • Amoxicillin

  • Ampicillin

  • Apixaban

  • Aprepitant

  • Armodafinil

  • Artemether/Lumefantrine

  • Atazanavir

  • Bosentan

  • Budesonide

  • Butabarbital

  • Butalbital

  • Chlorpropamide

  • Conivaptan

  • Cortisone

  • Cyclosporine

  • Darifenacin

  • Darunavir

  • Dasatinib

  • Dexamethasone

  • Dhea

  • Dicloxacillin

  • Dronedarone

  • Efavirenz

  • Eslicarbazepine Acetate

  • Ethinylestradiol

  • Etravirine

  • Fexofenadine

  • Fluconazole

  • Fludrocortisone

  • Fosamprenavir

  • Fosphenytoin

  • Ganaxolone

  • Grapefruit

  • Griseofulvin

  • Hydrocortisone

  • Indinavir

  • Ixazomib

  • Lapatinib

  • Loratadine

  • Lumefantrine

  • Marijuana

  • Methylprednisolone

  • Metronidazole

  • Miconazole

  • Nafcillin

  • Nelfinavir

  • Nevirapine

  • Nifedipine

  • Nilotinib

  • Oxacillin

  • Oxcarbazepine

  • Penicillin G Aqueous

  • Penicillin Vk

  • Pentobarbital

  • Phenobarbital

  • Phenytoin

  • Pivmecillinam

  • Posaconazole

  • Prednisone

  • Primidone

  • Quinupristin/Dalfopristin

  • Ramelteon

  • Rifapentine

  • Ritonavir

  • Rufinamide

  • Secobarbital

  • Temocillin

  • Theophylline

  • Ticarcillin

  • Topiramate

  • Valproic Acid

  • Verapamil

  • Voriconazole

  • Zafirlukast

  • Zaleplon

  • Zolpidem

ONYO: Usitumie dawa yoyote bila ushauri wa daktari. Dawa zinaweza kuleta madhara mwilini na pia matumizi ya baadhi ya dawa pasipo ushauri na vipimo husababisha  vimelea kuwa sugu dhidi ya dawa hiyo.
ULY clinic inakushauri kuwasiliana na daktari wako unapotaka kuchukua maamuzi yoyote yanayohusu afya yako.
Wasiliana na daktari/Mfamasia wa ULY clinic kwa ushauri na Tiba au kuandikiwa dawa kwa kupiga simu au Kubonyeza Pata tiba chini ya tovuti hii.

Imeboreshwa,

4 Juni 2022 20:57:49

Rejea za mada hii:-

1. Clarithromycin. https://www.medicines.org.uk/emc/product/6094/smpc#gref. Imechukuliwa 04.06.2022

2. Peters DH, Clissold SP. Clarithromycin. A review of its antimicrobial activity, pharmacokinetic properties and therapeutic potential. Drugs. 1992 Jul;44(1):117-64. doi: 10.2165/00003495-199244010-00009. PMID: 1379907.

3. Hardy DJ. Extent and spectrum of the antimicrobial activity of clarithromycin. Pediatr Infect Dis J. 1993 Dec;12(12 Suppl 3):S99-105. doi: 10.1097/00006454-199312003-00002. PMID: 8295818.

4. Zuckerman JM, et al. Macrolides, ketolides, and glycylcyclines: azithromycin, clarithromycin, telithromycin, tigecycline. Infect Dis Clin North Am. 2009 Dec;23(4):997-1026, ix-x. doi: 10.1016/j.idc.2009.06.013.

5. Niemi M, et al. The cytochrome P4503A4 inhibitor clarithromycin increases the plasma concentrations and effects of repaglinide. Clin Pharmacol Ther. 2001 Jul;70(1):58-65. doi: 10.1067/mcp.2001.116511.

6. Dalboge CS, et al: Pharmacokinetic variability of clarithromycin and differences in CYP3A4 activity in patients with cystic fibrosis. J Cyst Fibros. 2014 Mar;13(2):179-85. doi: 10.1016/j.jcf.2013.08.008. Epub 2013 Sep 10.

7. Akiyoshi T, et al. Mechanism-based inhibition profiles of erythromycin and clarithromycin with cytochrome P450 3A4 genetic variants. Drug Metab Pharmacokinet. 2013;28(5):411-5. Epub 2013 Mar 19.

8. Zhou S, et al. Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs. Clin Pharmacokinet. 2005;44(3):279-304. doi: 10.2165/00003088-200544030-00005.
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