By ULY CLINIC

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Gastroduodenal Ulcers (PUD)

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Introduction

 

Gastroduodenal Ulcers (PUD) is a disorder resulting from breakdown of mucosal defense mechanisms against hydrochloric acid and proteolytic enzymes, most commonly secondary to H.Pylori infection or NSAID use. 

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Diagnostic Criteria

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• Burning epigastric abdominal pains, usually relived by antacids.

• Anorexia, early satiety, bloating, 

• Hematemesis or melena stools

• Weight loss PLUS 

• Endoscopic evidence  of  gastric or duodenal  mucosal ulceration 

 

Pharmacological Treatment

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• Omeprazole (PO) 20mg once daily for 8 weeks

 OR

• Esomeprazole (PO) 20mg once daily for 8 weeks 

OR

• Pantoprazole (PO) 40mg once daily for 8 weeks. 

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Updated on, 2.11.2020

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References

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1. STG