Amoebiasis Treatment

Amoebiasis is an infection caused by the protozoan Entamoeba histolytica. It can cause colitis and extra-intestinal manifestations. Infection is primarily acquired through ingestion of contaminated food or water and may occasionally be acquired through oral-anal sexual practices.

Clinical Presentation

• Bloody diarrhea

• Crampy abdominal pain

• Fever

• Weight loss

• Peritonitis in severe forms

Investigations

• Stool saline wet mount demonstrating motile trophozoites or cysts of Entamoeba histolytica

Pharmacological Treatment

Metronidazole

• Dose: 400–800 mg

• Route: Oral (PO)

• Frequency: Every 8 hours

• Duration: 5 days

OR

Tinidazole

• Dose: 2 g

• Route: Oral (PO)

• Frequency: Every 24 hours

• Duration: 3 days