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By ULY CLINIC

Haemolytic Anaemia

Haemolytic anaemia results from an increase in the rate of red cell destruction in the intravascular or in the reticuloendothelial system in some pathological disorders 

Clinical Features: 

  • Pallor jaundice

  • Splenomegaly

  • Anaemia

  • Reticulocytosis

  • Indirect hyperbilirubinemia 

Note: After supportive treatment refer to higher health facility with adequate expertise and facilities 

Classification of haemolytic anaemia

Acquired haemolytic anaemias:

 

Immune

  • Autoimmune (warm antibody type, cold antibody)  

Alloimmune

  • Haemolytic transfusion reactions

  • HD

  • Allograft especially marrow transplantation 

 Red cell Fragmentation Syndromes

  • Arterial grafts, cardiac valve

  • Microangiopathic haemolytic anaemias  

Others

  • March haemoglobinuria

  • Infections (malaria, clostridia)

  • Chemicals and physical agents

Paroxysmal nocturnal haemoglobinulia 

Updated on, 27.10.2020

References

  1. STG 

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