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Malignant disease conditions 

Cancer is a term covering a wide range of malignant diseases, which contribute significantly to the overall morbidity and mortality of people worldwide. In this section you will learn about common malignant conditions in Africa and their management

Burkitt lymphoma

Burkitt lymphoma

Burkitt lymphoma (BL) is a highly aggressive mature B-cell non-Hodgkin lymphoma characterized by rapid cellular proliferation and a high tumour growth fraction. It is one of the fastest-growing human malignancies and constitutes a medical emergency requiring prompt diagnosis and initiation of treatment.

Acute lymphoblastic leukemia

Acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) is a malignant disorder of hematopoietic progenitor cells characterized by uncontrolled proliferation and accumulation of immature lymphoid precursor cells (lymphoblasts) in the bone marrow, peripheral blood, and extramedullary tissues.

Superior vena cava syndrome (SVCS)

Superior vena cava syndrome (SVCS)

uperior vena cava syndrome (SVCS) is a clinical syndrome resulting from partial or complete obstruction of blood flow through the superior vena cava (SVC). Approximately 90% of cases are caused by malignancy, making SVCS an important oncological emergency.Epidemiology

Anal cancer

Anal cancer

Anal cancer is a malignant tumour arising from the anal canal or perianal region. Although relatively uncommon compared with colorectal cancers, its incidence has increased globally, particularly among populations with human papillomavirus (HPV) infection and immunosuppression.

Cancer of the Ovary

Cancer of the Ovary

Ovarian cancer is a malignant neoplasm arising from the ovary and is one of the most lethal gynecological cancers. Epithelial tumors account for approximately 90% of all ovarian malignancies. Due to the deep anatomical location of the ovaries and the absence of specific early symptoms, most patients present with advanced disease.

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