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By ULYCLINIC
Introduction
Commonly presents as signs of peripheral neuropathy including:
• Tingling sensation
• Burning pain or numbness of the feet
Pyridoxine deficiency is related to:
• Malnutrition
• Alcoholism
• Isoniazid or combination TB therapy
Risk Factors
Signs and symptoms
Diagnostic criteria
Investigations
Managemet
-
Non-pharmacological
- Dietary advice:
Increase intake of pyridoxine rich foods such as:
• Liver, meat, fish and offal,
• Wholegrain cereals, fortified breakfast cereals,
• Peanuts, bananas, raw vegetables,
• Walnuts and seeds, avocados, dried fruits,
• Potatoes and baked beans.
-
Pharmacological
- For deficiency
Children:
• Pyridoxine 12.5mg (PO) daily for 3 weeks.
Adults:
• Pyridoxine, 25 mg (PO) daily for 3 weeks.
For medicine-induced neuropathy
Children
• Pyridoxine, 50mg (PO) daily for 3 weeks.
Adults
• Pyridoxine, 200mg (PO) daily for 3 weeks.
Then followed by:
• Pyridoxine, 25mg (PO) daily as maintenance dose (for patients on TB therapy/isoniazid)
Prevention
Updated on,
20 Novemba 2020 11:21:01
References
- 1. STG
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