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ULY CLINIC

ULY CLINIC

20 Septemba 2025, 01:21:15

Urinary urgency

Urinary urgency
Urinary urgency
Urinary urgency

Urinary urgency is the sudden, compelling desire to void that is difficult to defer. It may occur alone or with bladder pain, frequency, or incontinence. Urgency can be transient or chronic and often reflects irritation of the bladder mucosa, detrusor overactivity, or impaired neurologic control.


Pathophysiology

  • Bladder inflammation or irritation→ Mucosal edema and increased sensory nerve activity reduce bladder capacity and trigger involuntary contractions.

  • Neurologic dysfunction→ Lesions in the brain, spinal cord, or peripheral nerves (e.g., multiple sclerosis, spinal trauma) interrupt inhibitory pathways, producing detrusor hyperreflexia.

  • Obstructive or mechanical factors→ Bladder calculi, urethral strictures, or tumors cause incomplete emptying, increasing detrusor pressure.

  • Treatment-related irritation→ Radiation or intravesical agents may inflame the bladder wall.


History and Physical Examination

History
  • Onset: sudden vs. gradual, intermittent vs. constant

  • Associated urinary symptoms: dysuria, hematuria, cloudy urine, frequency, nocturia, hesitancy

  • Pain: suprapubic, flank, or referred (penis, vulva, low back)

  • Neurologic symptoms: paresthesia, weakness, gait changes, visual problems

  • Sexual & exposure history: recent intercourse (consider Reiter’s), use of bubble baths (children), radiation therapy

  • Past medical/surgical history: recurrent UTIs, neurologic disorders, pelvic or spinal procedures


Physical Examination
  • Inspect urethral meatus and external genitalia for inflammation, discharge, or lesions

  • Palpate the suprapubic region for bladder distention/tenderness

  • Percuss or palpate flanks for renal tenderness

  • Perform a focused neurologic exam: motor strength, tone, reflexes, sensation, gait

  • In children: examine perineal skin for irritation; assess for vulvovaginitis


Medical causes of urinary urgency

Cause

Onset

Key Features

Associated Findings

Pathophysiology

Management

Urinary tract infection (UTI)

Acute

Urgency, frequency, dysuria, hematuria, cloudy urine

Fever, chills, suprapubic/flank pain, nausea, vomiting

Bacterial invasion → mucosal inflammation & detrusor overactivity

Culture-guided antibiotics, hydration, analgesics (phenazopyridine)

Bladder calculus

Gradual or acute

Urgency, frequency, dysuria, terminal hematuria

Suprapubic pain radiating to perineum or back

Mucosal irritation and bladder spasm

Endoscopic or open removal, address cause

Multiple sclerosis

Gradual

Urgency, frequency ± incontinence

Visual loss, paresthesia, weakness, ataxia, hyperreflexia

CNS demyelination → loss of detrusor inhibition

Bladder training, anticholinergics, intermittent catheterization

Reiter’s syndrome (reactive arthritis)

Acute (1–2 wk post-sexual contact)

Urgency, dysuria

Conjunctivitis, arthritis (knees/ankles), oral or genital ulcers

Immune-mediated urethritis & bladder irritation

Treat infection, NSAIDs, supportive care

Spinal cord lesion

Acute or subacute

Urgency, frequency, retention

Weakness, paralysis, sensory changes, impotence

Disruption of supraspinal control → detrusor-sphincter dyssynergia

Intermittent catheterization, antimuscarinics, treat lesion

Urethral stricture

Gradual

Hesitancy, weak stream, urgency, nocturia

Overflow dribbling, bladder distention

Fibrotic narrowing → obstructed outflow & detrusor instability

Dilation, urethroplasty

Radiation cystitis

Gradual

Urgency, frequency, suprapubic discomfort

Hematuria, dysuria

Radiation-induced mucosal damage

Hydration, bladder instillations, avoid irritants


Other causes

  • Intravesical chemotherapy or BCG therapy

  • Bladder tumors (carcinoma in situ may present with irritative voiding)

  • Postoperative irritation (e.g., following transurethral procedures)


Emergency interventions

  • Acute urinary retention with urgency → Prompt bladder decompression via catheterization.

  • Neurologic lesion with overflow symptoms → Monitor residual volumes; consider intermittent catheterization.


Special considerations

  • Encourage adequate hydration unless contraindicated.

  • For irritative causes, avoid bladder irritants (caffeine, alcohol, acidic beverages).

  • Bladder retraining may benefit patients with detrusor overactivity.

  • Monitor urine output and residual volumes in neurologic or post-surgical patients.


Patient counseling

  • Teach proper perineal hygiene (front-to-back wiping in women).

  • Review safer sex and prompt STI treatment.

  • Explain Kegel or pelvic floor exercises for urgency associated with sphincter weakness.

  • Emphasize adherence to treatment for infections or neurologic disease.

  • Discuss lifestyle modifications: timed voiding, fluid management, avoiding bladder irritants.


Pediatric pointers

  • Sudden onset of urgency or daytime accidents in toilet-trained children may signal UTI or behavioral regression.

  • Bubble bath–related urethral irritation is a common benign cause.

  • Girls may present with vulvovaginitis or discharge; consider pinworm infestation.


Geriatric pointers

  • Older adults may present with urgency or incontinence as the first sign of UTI or delirium.

  • Age-related detrusor overactivity and reduced compliance increase urgency risk.

  • Evaluate for polypharmacy (diuretics, anticholinesterases) contributing to symptoms.


References
  1. Buttaro TM, Tybulski J, Bailey PP, Sandberg-Cook J. Primary Care: A Collaborative Practice. St. Louis (MO): Mosby Elsevier; 2008. p. 444-7.

  2. Colyar MR. Well-Child Assessment for Primary Care Providers. Philadelphia (PA): F.A. Davis; 2003.

  3. Sommers MS, Brunner LS. Pocket Diseases. Philadelphia (PA): F.A. Davis; 2012.

  4. Wein AJ, Kavoussi LR, Partin AW, Peters CA. Campbell-Walsh Urology. 12th ed. Philadelphia (PA): Elsevier; 2020.

  5. Abrams P, Cardozo L, Wagg A, Wein A, editors. Incontinence: 6th International Consultation on Incontinence. Bristol (UK): ICUD-EAU; 2017.

  6. Griebling TL. Urinary tract infection in women. N Engl J Med. 2020;382(10):948-57.

  7. Wyndaele JJ, Kovindha A, Madersbacher H, Radziszewski P, Ruffion A, Szabó L, et al. Neurological urinary and faecal incontinence. In: Abrams P, Cardozo L, Wagg A, Wein A, editors. Incontinence: 6th International Consultation on Incontinence. Bristol (UK): ICUD-EAU; 2017. p. 1445-530.

  8. Hanno PM, Erickson D, Moldwin R, Faraday MM. Diagnosis and treatment of interstitial cystitis/bladder pain syndrome. AUA Guideline. J Urol. 2011;185(6):2162-70.

  9. Grabe M, Bartoletti R, Bjerklund Johansen TE, Cai T, Çek M, Köves B, et al. Guidelines on urological infections. Arnhem (NL): European Association of Urology; 2022.

  10. Kessler TM, Fowler CJ, Panicker JN. Neurogenic lower urinary tract dysfunction in multiple sclerosis. Nat Rev Urol. 2009;6(5):255-66.

  11. McAninch JW, Lue TF. Smith & Tanagho’s General Urology. 20th ed. New York (NY): McGraw Hill; 2021.

  12. Stamm WE, Norrby SR. Urinary tract infections: disease panorama and challenges. J Infect Dis. 2001;183 Suppl 1:S1-4.

  13. Resnick NM, Yalla SV. Management of urinary incontinence in the elderly. N Engl J Med. 1985;313(14):800-5.

  14. Gormley EA, Lightner DJ, Faraday M, Vasavada SP. Diagnosis and treatment of overactive bladder (non-neurogenic) in adults: AUA/SUFU guideline amendment. J Urol. 2015;193(5):1572-80.

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