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ULY CLINIC
ULY CLINIC
20 Septemba 2025, 01:21:15
Urinary urgency
Urinary urgency is the sudden, compelling desire to void that is difficult to defer. It may occur alone or with bladder pain, frequency, or incontinence. Urgency can be transient or chronic and often reflects irritation of the bladder mucosa, detrusor overactivity, or impaired neurologic control.
Pathophysiology
Bladder inflammation or irritation→ Mucosal edema and increased sensory nerve activity reduce bladder capacity and trigger involuntary contractions.
Neurologic dysfunction→ Lesions in the brain, spinal cord, or peripheral nerves (e.g., multiple sclerosis, spinal trauma) interrupt inhibitory pathways, producing detrusor hyperreflexia.
Obstructive or mechanical factors→ Bladder calculi, urethral strictures, or tumors cause incomplete emptying, increasing detrusor pressure.
Treatment-related irritation→ Radiation or intravesical agents may inflame the bladder wall.
History and Physical Examination
History
Onset: sudden vs. gradual, intermittent vs. constant
Associated urinary symptoms: dysuria, hematuria, cloudy urine, frequency, nocturia, hesitancy
Pain: suprapubic, flank, or referred (penis, vulva, low back)
Neurologic symptoms: paresthesia, weakness, gait changes, visual problems
Sexual & exposure history: recent intercourse (consider Reiter’s), use of bubble baths (children), radiation therapy
Past medical/surgical history: recurrent UTIs, neurologic disorders, pelvic or spinal procedures
Physical Examination
Inspect urethral meatus and external genitalia for inflammation, discharge, or lesions
Palpate the suprapubic region for bladder distention/tenderness
Percuss or palpate flanks for renal tenderness
Perform a focused neurologic exam: motor strength, tone, reflexes, sensation, gait
In children: examine perineal skin for irritation; assess for vulvovaginitis
Medical causes of urinary urgency
Cause | Onset | Key Features | Associated Findings | Pathophysiology | Management |
Urinary tract infection (UTI) | Acute | Urgency, frequency, dysuria, hematuria, cloudy urine | Fever, chills, suprapubic/flank pain, nausea, vomiting | Bacterial invasion → mucosal inflammation & detrusor overactivity | Culture-guided antibiotics, hydration, analgesics (phenazopyridine) |
Bladder calculus | Gradual or acute | Urgency, frequency, dysuria, terminal hematuria | Suprapubic pain radiating to perineum or back | Mucosal irritation and bladder spasm | Endoscopic or open removal, address cause |
Multiple sclerosis | Gradual | Urgency, frequency ± incontinence | Visual loss, paresthesia, weakness, ataxia, hyperreflexia | CNS demyelination → loss of detrusor inhibition | Bladder training, anticholinergics, intermittent catheterization |
Reiter’s syndrome (reactive arthritis) | Acute (1–2 wk post-sexual contact) | Urgency, dysuria | Conjunctivitis, arthritis (knees/ankles), oral or genital ulcers | Immune-mediated urethritis & bladder irritation | Treat infection, NSAIDs, supportive care |
Spinal cord lesion | Acute or subacute | Urgency, frequency, retention | Weakness, paralysis, sensory changes, impotence | Disruption of supraspinal control → detrusor-sphincter dyssynergia | Intermittent catheterization, antimuscarinics, treat lesion |
Urethral stricture | Gradual | Hesitancy, weak stream, urgency, nocturia | Overflow dribbling, bladder distention | Fibrotic narrowing → obstructed outflow & detrusor instability | Dilation, urethroplasty |
Radiation cystitis | Gradual | Urgency, frequency, suprapubic discomfort | Hematuria, dysuria | Radiation-induced mucosal damage | Hydration, bladder instillations, avoid irritants |
Other causes
Intravesical chemotherapy or BCG therapy
Bladder tumors (carcinoma in situ may present with irritative voiding)
Postoperative irritation (e.g., following transurethral procedures)
Emergency interventions
Acute urinary retention with urgency → Prompt bladder decompression via catheterization.
Neurologic lesion with overflow symptoms → Monitor residual volumes; consider intermittent catheterization.
Special considerations
Encourage adequate hydration unless contraindicated.
For irritative causes, avoid bladder irritants (caffeine, alcohol, acidic beverages).
Bladder retraining may benefit patients with detrusor overactivity.
Monitor urine output and residual volumes in neurologic or post-surgical patients.
Patient counseling
Teach proper perineal hygiene (front-to-back wiping in women).
Review safer sex and prompt STI treatment.
Explain Kegel or pelvic floor exercises for urgency associated with sphincter weakness.
Emphasize adherence to treatment for infections or neurologic disease.
Discuss lifestyle modifications: timed voiding, fluid management, avoiding bladder irritants.
Pediatric pointers
Sudden onset of urgency or daytime accidents in toilet-trained children may signal UTI or behavioral regression.
Bubble bath–related urethral irritation is a common benign cause.
Girls may present with vulvovaginitis or discharge; consider pinworm infestation.
Geriatric pointers
Older adults may present with urgency or incontinence as the first sign of UTI or delirium.
Age-related detrusor overactivity and reduced compliance increase urgency risk.
Evaluate for polypharmacy (diuretics, anticholinesterases) contributing to symptoms.
References
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