Mwandishi:
Dkt. Mercy M, CO
Mhariri:
Dkt. Benjamin L, MD
Iloprost ni moja kati ya dawa inayotumika kutibu shinikizo la damu la juu la damu kwenye mapafu.
Majina ya kibiashara
Majina ya kibiashara ya Iloprost ni;
Ventavis
Iloprost ipo kundi gani la dawa?
Iloprost ni dawa iliyo katika kundi la Prostacyclin analogs.
Dawa zilizo kundi moja na Iloprost
Dawa zilizo kundi moja na Iloprost ni ;
Epoprostenol
Treprostinil
Fomu ya dawa ya Iloprost
Dawa hii ipo katika fomu ya;
Ampule ya kutumia mara moja (single use ampule)
Uzito wa dawa ya Iloprost
Iloprost ina uzito ufuatao;
Ampule ya kutumia mara moja
10mcg/ml (1ml)
20mcg/ml (1ml)
Iloprost hutibu nini?
Hutumika kutibu shinikizo la damu (pressure) iliyojuu kwenye mapafu (pulmonary arterial hypertension)
Namna Iloprost inavyoweza kufanya kazi
Prostaglandins zinapatikana kwenye tishu na majimaji ya mwilini na kupatanisha kazi za mwili. Iloprost ni moja wapo katika familia ya prostaglandins ambazo hutoka kwenye arachidonic acid. Kazi kubwa ya Iloprost ni kuzuia mkusanyiko wa platelet.
Ufyozwaji wa dawa
Kiwango cha dawa kinachoingia kwenye damu baada ya mtu kumeza dawa ni 63% na ufozwaji wake ufanyika haraka.
Mwingiliano wa Iloprost na chakula
Dawa hii inaweza kutumika mtu akiwa amepata chakula au akiwa hajapata chakula.
Wagonjwa wasiopaswa kutumia Iloprost
Wagonjwa wenye mzio wa Iloprost.
Wagonjwa wenye mzio wa dawa jamii ya prostacyclin analogs.
Utoaji taka wa Iloprost mwilini
Asilimia sitini na nane (68%) ya dawa hutolewa kwa njia ya mkojo na asilimia kumi na mbili (12%) hutolewa kwa njia ya haja kubwa.
Matumizi ya Iloprost kwa mama mjamzito
Hakuna tafiti zinazoonesha madhara ya dawa hii kwa mama mjamzito na mtoto aliye tumboni hivyo taadhari inatakiwa kuchukuliwa wakati mama anatumia dawa hii.
Matumizi ya Iloprost mama anayenyonyesha
Hakuna tafiti zinazoonesha madhara ya dawa hii kwa mama anayenyonyesha, kwa mtoto na katika uzalishwaji wa maziwa hivyo kimoja wapo kati ya mtoto kunyonya na mama kutumia dawa inatakiwa viangaliwe kulingana na uhitaji .
Dawa zenye muingiliano na Iloprost
Dawa zenye mwingiliano mkali na hivyo kutofaa kutumika pamoja na Iloprost
Lofexidine
Dawa zinazoweza kutumika na Iloprost chini ya uangalizi
Aldesleukin
Amifostine
Benazepril
Captopril
Carbidopa
Dabigatran
Eluxadoline
Epoprostenol
Fenoldopam
Fish oil triglycerides
Hydralazine
Ibrutinib
Levodopa
Minoxidil
Treprostinil
Xipamide
Dawa zenye mwingiliano mdogo na Iloprost
Agrimony
Brimonidine
Cornsilk
Forskolin
Maitake
Octacosanol
Reishi
Shepherd's purse
Tizanidine
Treprostinil
Maudhi madogo ya Iloprost
Maumivu ya tumbo
Kichefuchefu
Maumivu ya kichwa
Taya kuuma
Flushing
Maumivu ya misuli
Kichefuchefu
Maumivu ya mgongo
Syncope
Kukosa usingizi
Trismus
Shinikizo la damu kuwa chini
Mapigo ya moyo kuwa juu
Nimonia
Maumivu ya ulimi
Misuli kukaza
Hemoptysis
Ufanye nini endapo utasahau kutumia dozi yako?
Kama umesahau kutumia dozi yako tumia mara pale utakapokumbuka, kama muda wa dozi inayofata umekaribia usimeze dozi uliyosahau endelea na dozi inayofuata kwa muda uliopangiwa na daktari. Usimeze dozi mbili kufidia uliyosahau.
13 Juni 2023 19:18:46
Dawa Iloprost
Imeboreshwa,
29 Oktoba 2021 14:03:01
Dawa yoyote ni sumu, usitumie dawa pasipo ushauri wa daktari kuepuka madhara kwenye ogani mbalimbali kama figo na ini. Matumizi ya dawa pasipo ushauri wa daktari unaweza kusababisha madhara na usugu wa vimelea vya maradhi kwenye dawa.
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ULY CLINIC inakushauri siku zote uwasiliane na daktari wako kwa ushauri na tiba kabla ya kuchukua hatua yoyote ile baad aya kusoma makala hii.
Kupata ushauri zaidi na tiba kutoka kwa daktari wa ULY CLINIC bofya Mawasiliano yetu au Pata tiba.
Rejea za mada hii:
Bäck SE, et al. Age dependence of renal function: clearance of iohexol and p-amino hippurate in healthy males. Scand J Clin Lab Invest. 1989 Nov;49(7):641–646.
Bax RP, et al. The pharmacokinetics of meropenem in volunteers. J Antimicrob Chemother. 1989 Sep;24 (Suppl A):311–320.
Burman LA, et al. Pharmacokinetics of meropenem and its metabolite ICI 213,689 in healthy subjects with known renal metabolism of imipenem. J Antimicrob Chemother. 1991 Feb;27(2):219–224.
Christensson BA, et al. Pharmacokinetics of meropenem in subjects with various degrees of renal impairment. Antimicrob Agents Chemother. 1992 Jul;36(7):1532–1537.
DAVIES DF, SHOCK NW. Age changes in glomerular filtration rate, effective renal plasma flow, and tubular excretory capacity in adult males. J Clin Invest. 1950 May;29(5):496–507.
Douglas JG, et al. The pharmacokinetics of cefuroxime in the elderly. J Antimicrob Chemother. 1980 Jul;6(4):543–549.
Granerus G, et al. Reference values for 51Cr-EDTA clearance as a measure of glomerular filtration rate. Scand J Clin Lab Invest. 1981 Oct;41(6):611–616.
Harrison MP, et al. The disposition and metabolism of meropenem in laboratory animals and man. J Antimicrob Chemother. 1989 Sep;24 (Suppl A):265–277.
Jones RN, et al. In-vitro studies of meropenem. J Antimicrob Chemother. 1989 Sep;24 (Suppl A):9–29.
Krutzén E, et al. Plasma clearance of a new contrast agent, iohexol: a method for the assessment of glomerular filtration rate. J Lab Clin Med. 1984 Dec;104(6):955–961.
Ljungberg B, et al. Pharmacokinetics of antimicrobial agents in the elderly. Rev Infect Dis. 1987 Mar-Apr;9(2):250–264.