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Mwandishi:

Dkt. Mercy M, CO

Mhariri:

Dkt. Mangwella S, MD

kirusi mumps-ulyclinic

Sildenafil ni moja kati ya dawa inayotumika kutibu matatizo ya kushindwa kusimamisha uume au kusimamisha kwa muda mfupi na kushusha shinikizo la la juu la damu kwenys mapafudamu iliyojuu kwenye mapafu.


Majina ya kibiashara


Majina mengine ya kibiashara ya sildenafil ni;


  • Revatio

  • Viagra


Sildenafil ipo kundi gani la dawa?


Sildenafil ni dawa iliyo katika kundi la PAH, PDE-5 Inhibitors; Phosphodiesterase-5 Enzyme Inhibitors.


Dawa zilizo kundi moja na Sildenafil


Dawa zilizo kundi moja na Sildenafil ni ;


  • Vardenafil

  • Tadalafil

  • Avanafil


Fomu ya Sildenafil


Dawa hii ipo katika fomu ya;


  • Kidonge

  • Solusheni kwaajiri ya sindano

  • Solusheni kwaajiri ya kunywa


Uzito wa Sildenafil


Sildenafil ina uzito ufuatao;


Vidonge (Revatio)


  • 20mg


Vidonge (Viagra)


  • 25mg

  • 50mg

  • 100mg


Solusheni kwaajiri ya sindano


  • 10mg/12.5ml


Kimiminika cha kunywa


  • 10mg/ml


Sildenafil hutibu nini?


  • Hutumika kutibu matatizo kwa wanaume wasio na uwezo wa kusimamisha uume kwa muda mrefu

  • Hutumika kutibu shinikizo la damu iliyojuu kwenye mapafu.


Namna Sildenafil inavyoweza kufanya kazi


Sildenafil hufanya kazi ya kuzuia PDE-5 hivyo kuongeza cyclic guanosine monophosphate cGMP na kuruhusu mishipa iweze kutanuka.





Ufyozwaji wa dawa


Ufyozwaji wa dawa hii hufanyika vizuri kwenye mfumo wa chakula, kiwango cha dawa kinachoonekana kwenye damu baada ya kutumia ni 40% na huanza kuonekana kwenye damu ndani ya dakika 30-120 baada ya mtu kumeza dawa.


Mwingiliano wa Sildenafil na chakula


Dawa hii inaweza kutumika mtu akiwa amepata chakula au akiwa hajapata chakula.


Wagonjwa wasiopaswa kutumia Sildenafil


  • Wagonjwa wenye mzio wa Sildenafil.

  • Wagonjwa wenye mzio wa dawa jamii ya PDE-5 Inhibitors; Phosphodiesterase-5 Enzyme inhibitors.


Utoaji taka wa Saldenafil mwilini


Asilimia themanini (80%) ya dawa hii hutolewa kwa njia ya haja kubwa na asilimia kumi na tatu (13%) hutolewa kwa njia ya mkojo.


Matumizi ya Sildenafil kwa mama mjamzito


Hakuna tafiti zinazoonesha madhara ya dawa hii kwa mama mjamzito lakini mwanamke mwenye matatizo ya moyo asipotibiwa anaweza anakuwa kwenye hatari ya kujifungua kabla ya muda pia mama kuwa kwenye hatari ya kifo.


Matumizi ya Sildenafil kwa mama anayenyonyesha


Hakuna tafiti zinazoonesha kuwa dawa hii inaweza kuleta madhara kwa mama anayenyonysha, kwa mtoto anayenyosha na katika uzalishwaji wa maziwa.


Dawa zenye muingiliano na Sildenafil



Dawa zenye mwingiliano mkali na hivyo kutofaa kutumika pamoja na Sildenafil

  • Abametapir

  • Alfuzosin

  • Amyl nitrite

  • Apalutamide

  • Asenapine

  • Chloramphenicol

  • Clarithromycin

  • Conivaptan

  • Crizotinib

  • Dabrafenib

  • Doxazosin

  • Eslicarbazepine acetate

  • Fexinidazole

  • Glyceryl trinitrate pr

  • Ivosidenib

  • Ketoconazole

  • Lonafarnib

  • Lopinavir

  • Mifepristone

  • Mitotane

  • Nafcillin

  • Ombitasvir/paritaprevir/ritonavir & dasabuvir

  • Oxcarbazepine

  • Pentobarbital

  • Phenobarbital

  • Phenoxybenzamine

  • Phentolamine

  • Phenytoin

  • Prazosin

  • Primidone

  • Ritonavir

  • Silodosin

  • St john's wort

  • Terazosin

  • Tucatinib

  • Voxelotor


Dawa zinazoweza kutumika na Sildenafil chini ya uangalizi

  • Acebutolol

  • Amifostine

  • Artemether/lumefantrine

  • Atenolol

  • Benazepril

  • Captopril

  • Carbamazepine

  • Carvedilol

  • Cenobamate

  • Cimetidine

  • Cyclosporine

  • Darunavir

  • Deferasirox

  • Dexamethasone

  • Efavirenz

  • Epoprostenol

  • Erythromycin base

  • Griseofulvin

  • Idelalisib

  • Iloperidone

  • Indinavir

  • Isoniazid

  • Istradefylline

  • Itraconazole

  • Labetalol

  • Lapatinib

  • Lesinurad

  • Letermovir

  • Levamlodipine

  • Lorlatinib

  • Maraviroc

  • Metoprolol

  • Miconazole vaginal

  • Nebivolol

  • Nefazodone

  • Nevirapine

  • Nifedipine

  • Nilotinib

  • Nitroprusside sodium

  • Penbutolol

  • Pindolol

  • Posaconazole

  • Propranolol

  • Ribociclib

  • Rifabutin

  • Rifampin

  • Voriconazole


Dawa zenye mwingiliano mdogo na Sildenafil;

  • Labetalol

  • Macitentan

  • Sapropterin


Maudhi madogo ya Sildenafil


  • Maumivu ya kichwa

  • kichefuchefu

  • Kutokwa na jasho

  • Kukosa usingizi

  • Kutokwa damu puani

  • Kiungulia

  • Kizunguzungu

  • Wekundu kwenyengozi

  • Kuharisha

  • kizunguzungu

  • Vipele kwenye ngozi


Ufanye nini endapo utasahau kutumia dozi yako?


Ni muhimu sana kutumia dozi yako kwa wakati sahihi.Kama umesahau kutumia dozi yako kwa wakati sahihi wasiliana na daktari wako au mfamasia akupe maelekezo ya dozi inayofuata.


13 Juni 2023 19:18:46

Dawa Sildenafil

Imeboreshwa,

30 Oktoba 2021 18:29:27

Dawa yoyote ni sumu, usitumie dawa pasipo ushauri wa daktari kuepuka madhara kwenye ogani mbalimbali kama figo na ini. Matumizi ya dawa pasipo ushauri wa daktari unaweza kusababisha madhara na usugu wa vimelea vya maradhi kwenye dawa.

ULY CLINIC inakushauri siku zote uwasiliane na daktari wako kwa ushauri na tiba kabla ya kuchukua hatua yoyote ile baad aya kusoma makala hii.

Kupata ushauri zaidi na tiba kutoka kwa daktari wa ULY CLINIC bofya Mawasiliano yetu au Pata tiba.

Rejea za mada hii:

  1. Bäck SE, et al. Age dependence of renal function: clearance of iohexol and p-amino hippurate in healthy males. Scand J Clin Lab Invest. 1989 Nov;49(7):641–646.

  2. Bax RP, et al. The pharmacokinetics of meropenem in volunteers. J Antimicrob Chemother. 1989 Sep;24 (Suppl A):311–320.

  3. Burman LA, et al. Pharmacokinetics of meropenem and its metabolite ICI 213,689 in healthy subjects with known renal metabolism of imipenem. J Antimicrob Chemother. 1991 Feb;27(2):219–224.

  4. Christensson BA, et al. Pharmacokinetics of meropenem in subjects with various degrees of renal impairment. Antimicrob Agents Chemother. 1992 Jul;36(7):1532–1537. 

  5. DAVIES DF, SHOCK NW. Age changes in glomerular filtration rate, effective renal plasma flow, and tubular excretory capacity in adult males. J Clin Invest. 1950 May;29(5):496–507.

  6. Douglas JG, et al. The pharmacokinetics of cefuroxime in the elderly. J Antimicrob Chemother. 1980 Jul;6(4):543–549.

  7. Granerus G, et al. Reference values for 51Cr-EDTA clearance as a measure of glomerular filtration rate. Scand J Clin Lab Invest. 1981 Oct;41(6):611–616.

  8. Harrison MP, et al. The disposition and metabolism of meropenem in laboratory animals and man. J Antimicrob Chemother. 1989 Sep;24 (Suppl A):265–277. 

  9. Jones RN, et al. In-vitro studies of meropenem. J Antimicrob Chemother. 1989 Sep;24 (Suppl A):9–29. 

  10. Krutzén E, et al. Plasma clearance of a new contrast agent, iohexol: a method for the assessment of glomerular filtration rate. J Lab Clin Med. 1984 Dec;104(6):955–961.

  11. Ljungberg B, et al. Pharmacokinetics of antimicrobial agents in the elderly. Rev Infect Dis. 1987 Mar-Apr;9(2):250–264.

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