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Mwandishi:

Dkt. Sospeter M, MD

Mhariri:

Dkt. Lugonda B, MD

28 Machi 2021 14:53:38

Dawa Isoniazid

Dawa Isoniazid

Isoniazid ni miongoni mwa dawa zinazotumika katika matibabu na kinga ya maambukizi ya kifua kikuu (TB), dawa hii ipo


Fomu na uzito wa isoniazid


• Dawa hii hupatikana kwenye fomu mbalimbali ambazo ni • Vidonge vya uzito wa miligramu 50, 100 na 300 • Dawa ya maji ya kunywa yenye uzito wa miligwamu 10 kwa kila mililita 1 ya maji • Dawa ya maji kwa ajili ya kuchoma- miligramu100 kwa kili mililita ya maji


Namna isoniazid inavyofanya kazi kutibu TB


Ufanyaje kazi wake haujulikani, inahisiwa kuzuia uzalishaji wa vijenzi vya kuta za bakteria kwa kuzuia uzalishaji wa mafuta na DNA ya bakteria kwa kufanya hivi, hupelekea kufa kwa bakteria


Ufyonzwaji wa isoniazid


Mara baada ya kunywa na kuingia tumbini, dawa hii hufyonzwa kirahisi na kuingia kwenye damu ndani ya saa 1 hadi 2


Utoaji taka mwilini wa dawa isoniazid


Dawa baada ya kuvunjwa na ini hutolewa mwilini kwa njia ya kinyesi kwa asilimia 75 hadi 95


Matumizi ya dawa isoniazid


Isoniazid hutumika pamoja na dawa zingine za Kifua kikuu kutibu • Maambukizi hai ya TB • Kinga ya maambukizi ya kifua kikuu kwa watu walio hatarini kupata Tb kama wale wanaohudumia wagonjwa wa TB hospitali au nyumbani


Namna ya kutumia isoniazid


Tumia dawa hii bila chakula, au saa 1 kabla ya kula au masaa 2 baada ya kula kama ulivyoelekezwa na daktari wako


Isoniazid Haifai kutumika kwa wagonjwa wafuatao


• Waliodhuriwa ini walipotumia kwa mara ya kwanza • Ugonjwa wa muda mfupi wa ini • Wenye ugonjwa wa pancreatitis • Wenye mzio na dawa hii


Maudhi ya dawa isoniazid


Nyuropathi ya pembeni(hisia za ganzi, miguu na mikono kuchomachoma n.k)

• Kukosa hau ya kula • Kichefuchefu • Kutapika • Maumivu ya tumbo • Udhaifu wa mwili • Kizunguzungu • Kuongea kama mlevi • Uchovu mkali wa mwili • Kuharibika endelevu kwa ini • Kuongezeka kwa rifleksi • Upungufu wa neutrophil • Kupungua kwa chembe nyeupe za damu • Upungufu wa damu • Upungufu wa chembe sahani za damu • Upungufu wa damu wa Megaloblastic • Lupus erythematosus • Degedege


Matumizi ya isoniazid kwenye ujauzito


Inatakiwa kutumika kwa tahadhari wakati wa ujauzito. Soma maelezo zaidi katika sehemu ya matumizi ya Isoniazid kipindi cha ujauzito na kunyonyesha sehemu nyingine katika tovuti ya ULY CLINIC


Matumizi ya isoniazid kipindi cha kunyonyesha


Ni salama kwa wamama wanaonyonyesha, kwa maelezo zaidi soma kuhusu matumizi ya Isoniazid kipindi cha ujauzito na kunyonyesha sehemu nyingine katika tovuti ya ULY CLINIC


Dawa ambazo hazipaswi kutumika na Isoniazid


• Acalabrutinib • Ado-trastuzumab emtansine • Alfentanil • Alfuzosin • Avanafil • Avapritinib • Axitinib • Bedaquiline • Bosutinib • Brigatinib • Cabazitaxel • Cabozantinib • Ceritinib • Cilostazol • Clopidogrel • Cobimetinib • Conivaptan • Copanlisib • Dabrafenib • Desvenlafaxine • Dihydroergotamine • Dihydroergotamine intranasal • Dronedarone • Eliglustat • Encorafenib • Entrectinib • Eplerenone • Erdafitinib • Ergotamine • Erythromycin base • Erythromycin ethylsuccinate • Erythromycin lactobionate • Erythromycin stearate • Esomeprazole • Etravirine • Everolimus • Fedratinib • Fentanyl • Fentanyl intranasal • Fentanyl transdermal • Fentanyl transmucosal • Flibanserin • Fluticasone intranasal • Gilteritinib • Glasdegib • Ibrutinib • Idelalisib • Irinotecan • Irinotecan liposomal • Isocarboxazid • Ivabradine • Ketoconazole • Lefamulin • Lemborexant • Linezolid • Lomitapide • Lonafarnib • Lorcaserin • Lorlatinib • Lovastatin • Lurasidone • Lurbinectedin • Macitentan • Methylene blue • Midazolam intranasal • Midostaurin • Mirtazapine • Naloxegol • Neratinib • Nilotinib • Nisoldipine • Olaparib • Omeprazole • Osimertinib • Oxycodone • Palbociclib • Pemigatinib • Pexidartinib • Phenelzine • Pimavanserin • Pimozide • Pomalidomide • Ponatinib • Pralsetinib • Pretomanid • Ranolazine • Red yeast rice • Regorafenib • Rifampin • Rimegepant • Riociguat • Ruxolitinib • Selumetinib • Silodosin • Simvastatin • Siponimod • Sirolimus • Sonidegib • Suvorexant • Tamsulosin • Tazemetostat • Tizanidine • Tofacitinib • Tolvaptan • Trabectedin • Tranylcypromine • Vemurafenib • Venetoclax • Vilazodone • Voclosporin • Vorapaxar • Voxelotor


Dawa zinazohitaji uangalizi wa karibu ufanyike na dawa zenye mwingiliano mdogo sana na Isoniazid


Endapo isoniazidi itatumika kwa pamoja na dawa hizi, uchunguzi wa karibu ufanyike • 5-htp • Abemaciclib • Abiraterone • Acetaminophen • Acetaminophen a kuweka njia ya haja kubwa • Acetaminophen ya mishipa • Alitretinoin • Almotriptan • Alosetron • Alprazolam • Aluminum hydroxide • Amifampridine • Amiodarone • Amitriptyline • Amoxapine • Apalutamide • Aprepitant • Aripiprazole • Armodafinil • Artemether/lumefantrine • Atazanavir • Atorvastatin • Benzhydrocodone/acetaminophen • Bexarotene • Bortezomib • Bosentan • Brentuximab vedotin • Brexpiprazole • Budesonide • Buprenorphine a kupandikiza chini ya ngozi • Buprenorphine, a kuchoma inayofanya kazi muda mrefu • Buspirone • Calcifediol • Calcium carbonate • Cannabidiol • Carbamazepine • Cariprazine • Cevimeline • Cilostazol • Cimetidine • Cinacalcet • Citalopram • Clarithromycin • Clobazam • Clobetasone • Clomipramine • Clopidogrel • Clorazepate • Clozapine • Cobicistat • Cocaine • Codeine • Cortisone • Crizotinib • Cycloserine • Dapsone • Darifenacin • Darunavir • Dasatinib • Deflazacort • Desipramine • Dexamethasone • Dexfenfluramine • Dextroamphetamine • Dextromethorphan • Diazepam • Diazepam intranasal • Dichlorphenamide • Dienogest/estradiol valerate • Dihydroergotamine • Dihydroergotamine a kuweka kwenye pua • Disopyramide • Disulfiram • Docetaxel • Doravirine • Doxepin • Doxorubicin • Doxorubicin liposomal • Dronabinol • Duloxetine • Dutasteride • Efavirenz • Elagolix • Eletriptan • Eltrombopag • Eluxadoline • Elvitegravir • Elvitegravir/cobicistat/emtricitabine/tenofovir df • Enfortumab vedotin • Ergotamine • Erlotinib • Escitalopram • Estradiol a kuweka ukeni • Ethanol • Ethionamide • Etonogestrel • Etoposide • Etravirine • Felodipine • Fenfluramine • Fesoterodine • Finasteride • Flibanserin • Fludrocortisone • Fluoxetine • Fluticasone furoate ya kuvuta puani • Fluticasone inhaled • Fluvoxamine • Fosamprenavir • Frovatriptan • Galantamine • Gefitinib • Glecaprevir/pibrentasvir • Green tea • Guanfacine • Haloperidol • Hydrocodone • Hydrocortisone • Hydroxyprogesterone caproate • Iloperidone • Imatinib • Imipramine • Indinavir • Insulin degludec • Insulin degludec/insulin aspart • Insulin inhaled • Isradipine • Istradefylline • Itraconazole • Ivacaftor • Ixabepilone • Lacosamide • Lansoprazole • Lapatinib • Levamlodipine • Levodopa inhaled • Levomilnacipran • Levonorgestrel oral/ethinylestradiol/ferrous bisglycinate • Lidocaine • Lithium • Lofepramine • Lopinavir • Loratadine • Lsd • L-tryptophan • Lumacaftor/ivacaftor • Lumefantrine • Maprotiline • Maraviroc • Medroxyprogesterone • Mefloquine • Meperidine • Metformin • Methadone • Methylprednisolone • Metronidazole • Mexiletine • Midazolam • Milnacipran • Mipomersen • Mirtazapine • Morphine • Naldemedine • Naratriptan • Nefazodone • Nelfinavir • Netupitant/palonosetron • Nicardipine • Nifedipine • Nimodipine • Nitrendipine • Nortriptyline • Olanzapine • Oliceridine • Ondansetron • Osilodrostat • Ospemifene • Paclitaxel • Paclitaxel protein bound • Panobinostat • Paroxetine • Pazopanib • Pentazocine • Pimozide • Polatuzumab vedotin • Prednisolone • Prednisone • Propafenone • Protriptyline • Quetiapine • Quinidine • Quinine • Ramelteon • Rasagiline • Repaglinide • Rilpivirine • Riluzole • Ripretinib • Ritonavir • Rizatriptan • Romidepsin • Ropinirole • Safinamide • Same • Saquinavir • Saxagliptin • Selegiline • Selegiline transdermal • Sertraline • Sevoflurane • Sildenafil • Sodium bicarbonate • Sodium citrate/citric acid • Sodium picosulfate/magnesium oxide/anhydrous citric acid • Sodium sulfate/magnesium sulfate/potassium chloride • Sodium sulfate/potassium sulfate/magnesium sulfate • Solifenacin • St john's wort • Sufentanil • Sufentanil sl • Sumatriptan • Sumatriptan intranasal • Sunitinib • Tacrolimus • Tadalafil • Tamoxifen • Tamsulosin • Tasimelteon • Temsirolimus • Terbinafine • Tezacaftor • Theophylline • Tipranavir • Tofacitinib • Tolterodine • Toremifene • Tramadol • Trazodone • Triamcinolone acetonide kimiminika cha kuchoma • Triazolam • Trimipramine • Ubrogepant • Umeclidinium bromide/vilanterol a kuvuta njia ya hewa • Upadacitinib • Valbenazine • Vardenafil • Venlafaxine • Verapamil • Vilanterol/fluticasone furoate a kuvuta puani • Vinblastine • Vincristine • Vincristine liposomal • Vinorelbine • Voriconazole • Warfarin • Zanubrutinib • Zolmitriptan • Zonisamide Isoniazid ina mwingiliano mdogo sana na dawa zifuatazo • Acarbose • Acetaminophen • Acetaminophen iv • Acetaminophen ya kuweka njia ya haja kubwa • Ambrisentan • Amitriptyline • Antipyrine • Asenapine • Bazedoxifene/conjugated estrogens • Budesonide • Caffeine • Calcium acetate • Calcium carbonate • Calcium chloride • Calcium citrate • Calcium gluconate • Chlorpropamide • Clomipramine • Conjugated estrogens • Conjugated estrogens, a kuweka ukeni • Cortisone • Deflazacort • Desipramine • Dexamethasone • Didanosine • Donepezil • Estradiol • Estrogens conjugated synthetic • Estrogens esterified • Estropipate • Ethanol • Ethotoin • Eucalyptus • Fludrocortisone • Food • Fosphenytoin • Glimepiride • Glipizide • Glyburide • Hydrocortisone • Imipramine • Insulin aspart • Insulin detemir • Insulin glargine • Insulin glulisine • Insulin lispro • Insulin nph • Insulin regular human • Ixazomib • Ketoconazole • Mestranol • Methylprednisolone • Miglitol • Montelukast • Nateglinide • Niacin • Oxybutynin • Parecoxib • Phenytoin • Pioglitazone • Prednisolone • Prednisone • Primaquine • Pyrazinamide • Pyridoxine • Pyridoxine (antidote) • Rabeprazole • Ramelteon • Repaglinide • Rosiglitazone • Sitagliptin • Tolazamide • Tolbutamide • Triamcinolone acetonide injectable suspension • Valproic acid • Vildagliptin • Zaleplon • Ziprasidone • Zolpidem


Endapo umesahau dozi ya isoniazid ufanyaje


Endapo umesahau kutumia dozi yako, tumia mara pale utakapokumbuka, na endapo muda wa dozi nyingine umekaribia sana, acha dozi uliyosahau na subiria muda wa dozi nyingine ufike kisha endelea kwa jinsi ulivyoelekezwa na daktari wako.

ONYO: Usitumie dawa yoyote bila ushauri wa daktari. Dawa zinaweza kuleta madhara mwilini na pia matumizi ya baadhi ya dawa pasipo ushauri na vipimo husababisha  vimelea kuwa sugu dhidi ya dawa hiyo.
ULY clinic inakushauri kuwasiliana na daktari wako unapotaka kuchukua maamuzi yoyote yanayohusu afya yako.
Wasiliana na daktari/Mfamasia wa ULY clinic kwa ushauri na Tiba au kuandikiwa dawa kwa kupiga simu au Kubonyeza Pata tiba chini ya tovuti hii.

Imeboreshwa,

23 Julai 2023 16:54:56

Rejea za mada hii:-

1. Matumizi ya isoniazid wakati wa ujauzito na kunyonyesha @ ulyclinic

2. Isoniazid. https://go.drugbank.com/drugs/DB00951. Imechukuliwa 28.03.2021

3. PubChem . Isoniazid C6H7N3O. https://pubchem.ncbi.nlm.nih.gov/compound/Isoniazid. Imechukuliwa 28.03.2021

4. FDA. Isoniazid Tablets, USP WARNING DESCRIPTION. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/008678s028lbl.pdf. Imechukuliwa 28.03.2021

5. FDA. RIFATER (rifampin, isoniazid and pyrazinamide USP). https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/050705s011lbl.pdf. Imechukuliwa 28.03.2021

6. Isoniazid. Courtney O'Connor, et al. https://www.ncbi.nlm.nih.gov/books/NBK557617/. Imechukuliwa 28.03.2021

7. Isoniazid toxicity. Madhuri Badrinath, et al. https://www.ncbi.nlm.nih.gov/books/NBK531488/. Imechukuliwa 28.03.2021
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