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Vitamin B3/Nicotinic Acid Deficiency (Pellagra)

By ULYCLINIC

Introduction

Pellagra is a condition associated with nicotinic acid deficiency. It is usually accompanied by other vitamin deficiencies.

Risk Factors

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Signs and symptoms

• Diarrhoea
• Dementia
• Dermatitis with darkening of sun-exposed skin

Diagnostic criteria

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Investigations

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Managemet

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  • Non-pharmacological

    • Lifestyle adjustment including discouraging of alcohol abuse.

    Dietary advice:

    Increase intake of

    • Liver, kidneys, other meats, poultry and fish
    • Peanuts
    • Milk
    • Pulses, whole meal wheat and bran

  • Pharmacological

    For severe deficiency

    Children

    • Nicotinamide, oral, 50 mg 8 hourly for one week.

    Adults

    • Nicotinamide, oral, 100 mg 8 hourly for one week.

    For mild deficiency

    Children

    • Nicotinamide, oral, 50 mg daily for one week.

    Adults

    • Nicotinamide, oral, 100 mg daily for one week.

Prevention

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Updated on,

20 Novemba 2020 11:16:41

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References

    1. STG
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