Skin diseases and allergic reactions
Urticaria and angioedema Treatment
Urticaria and angioedema are common hypersensitivity disorders characterized by recurrent episodes of transient wheals (hives) with or without deeper swelling of the skin and mucous membranes (angioedema). Urticaria results from the release of histamine and other inflammatory mediators from mast cells, leading to localized edema of the superficial skin. Angioedema involves deeper layers of the skin and subcutaneous tissues and commonly affects the lips, tongue, eyelids, and throat.
Localized and systemic scleroderma Treatment
Scleroderma is a chronic autoimmune connective tissue disease characterized by excessive collagen deposition leading to fibrosis of the skin and, in systemic disease, internal organs. The exact cause is unknown, but genetic susceptibility, immune dysregulation, and vascular injury contribute to disease development.
