By ULY CLINIC
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Treatment of Tuberculosis in Special Cases
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Treatment of TB/HIV co-infected patients
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Consideration is needed when handling a patient with TB/HIV co-infection.
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Special considerations for ART in TB/HIV co-infected patients
Also, the following shall be considered in treatment of TB patients:
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Pregnancy:
Anti-TB is safe during pregnancies except streptomycin, which causes permanent deafness in the fetus therefore it should be avoided during pregnancy.
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Breast feeding:
In the mothers with pulmonary tuberculosis, the baby should receive INH preventive (5mg/kg) for 6 months followed A: BCG vaccination.
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Oral contraceptives: Rifampicin interacts with oral contraceptives and reduces the efficacy of this contraception.
Liver disease:
Most of anti-TB medicines can cause liver damage. In case a patient develops jaundice, treatment should be stopped and restarted as soon as the jaundice resolves. In severely ill patients, start streptomycin and ethambutol only.
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Renal failure:
Streptomycin and ethambutol are excreted by the kidneys and should either be avoided or given in a reduced dose.
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Updated on, 31.10.2020
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References
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1. STG page number 10-12